Core F: Research Education Component (RL5)

核心F：研究教育部分(RL5) 摘要 阿尔茨海默病(AD)和其他痴呆症是复杂的、多维的实体。开发有效的 治疗和预防策略将需要将知识和专业知识整合到整个翻译 从基础科学研究到实施研究。实现这一目标需要一个新的 新一代研究人员具有特定领域的专业知识，对其他学科有广泛的知识 与痴呆症相关，以及对跨学科工作的强烈导向。研究性教育 Component(REC)准备聘请密歇根州ADCC的核心领导人和专家团队 与选定的研究员和初级教员进行整合的指导方法。与其他ADCC合作 在现有R25和T32机制的基础上，REC将实施跨学科指导 为选定的研究员和初级教员提供的课程。REC的首要目标是识别和指导 翻译领域内与痴呆症相关的跨学科研究方面有才华的初级调查人员。 REC的目标是招募有才华的初级研究人员参与痴呆症研究，以提高初级 调查员研究技能，为研究员和初级教员在他们职业生涯的早期阶段配备 广泛的痴呆症知识，帮助初级调查人员发展关键的实践技能 制作成功的助学金申请，并由经验丰富的人提供一般职业指导 调查人员。为实现这些目标提出了五个具体目标。目标1：招募有才华的初级员工 跨学科痴呆症研究的调查人员；目标2：提高初级调查人员的研究技能；目标 3：开发一个全面的、跨学科的课程，教育初级调查人员有关广泛的知识 痴呆症研究的范围；目标4：提供关键职业技能的实践培训，包括赠款 准备和口头陈述技能；和目标5：增强调查人员在以下方面工作的多样性 痴呆症相关研究。REC将通过利用可在 密歇根ADCC核心，以及数量非凡的才华横溢的高级调查人员和丰富的职业生涯 组成ADCC的三所大学提供的发展资源。特别是，REC 与密歇根城市非洲裔美国人老龄化研究中心合作的拉美裔美国人研究- 神经认知老化调查(SOL-INCA)项目和克劳德·D·佩珀老年美国人 独立中心将在实现这五个目标方面发挥重要作用。许多初级调查员候选人都有 已经确定，其中五人被认为是第一年强有力的REC候选人，并得到指导 他们的职业发展计划被作为未来可再生能源活动的范例。

CORE F: RESEARCH EDUCATION COMPONENT (RL5) Abstract Alzheimer’s disease (AD) and other dementias are complex, multidimensional entities. Developing effective therapies and prevention strategies will require integration of knowledge and expertise across the translational spectrum, from basic science research to implementation research. Accomplishing this goal requires a new generation of investigators possessing domain-specific expertise, broad knowledge of other disciplines relevant to the dementias, and strong orientation towards interdisciplinary work. The Research Education Component (REC) is poised to employ the Michigan ADCC’s Core leaders and teams of experts in an integrated mentoring approach with selected fellows and junior faculty. In collaboration with the other ADCC Cores and building on existing R25 and T32 mechanisms, the REC will implement inter-disciplinary mentoring programs for selected fellows and junior faculty. The overarching goal of the REC is to identify and mentor talented junior investigators in interdisciplinary dementia-related research across the translational spectrum. The objectives of the REC are to recruit talented junior investigators into dementia research, to enhance junior investigator research skills, to equip fellows and junior faculty at the earliest stages of their careers with a broad knowledge of dementias, to assist junior investigators with development of crucial practical skills in crafting successful grant support applications, and to provide general career mentorship by experienced investigators. Five specific aims are proposed to achieve these objectives. Aim 1: Recruit talented junior investigators into interdisciplinary dementia research; Aim 2: Enhance junior investigator research skills; Aim 3: Develop a comprehensive, interdisciplinary curriculum to educate junior investigators about the broad spectrum of dementia research; Aim 4: Provide practical training in crucial career skills including grant preparation and oral presentation skills; and Aim 5: Enhance the diversity of investigators working on dementia-related research. The REC will achieve its aims by drawing on the diverse expertise available in the Michigan ADCC Cores, and the extraordinary number of talented senior investigators and abundant career development resources available at the three universities comprising the ADCC. In particular, REC collaborations with the Michigan Center for Urban African American Aging Research, the Study of Latinos- Investigation of Neurocognitive Aging (SOL-INCA) project, and the Claude D. Pepper Older American Independent Center will be instrumental in achieving these five goals. Many candidate junior investigators have already been identified, of whom five are presented as strong REC candidates for year one, with mentoring plans for their career development offered as examples of future REC activities.