(1/2) University of Guam/University of Hawaii Cancer Center Partnership

项目摘要/摘要：太平洋岛民血统的美国人是一个高度缺乏服务的少数民族，他们的癌症负担非常严重。此外，他们在癌症研究人员和癌症保健专业人员中的代表性也很低。关岛大学（UOG）和夏威夷大学癌症中心（UHCC）在过去12年中建立了独特而成功的伙伴关系，目前得到U54赠款的支持。作为解决太平洋岛民癌症健康差异的唯一U54伙伴关系，UOG/UHCC伙伴关系的特点是具有许多非常独特的方面和机会。特别是，37%的关岛人口是土著查莫罗人/部分查莫罗人，38%是菲律宾人和密克罗尼西亚人。UOG/UHCC伙伴关系的独特民族特征与其独特的地理特征（HI、GU和美国太平洋地区/司法管辖区所覆盖的地区）以及独特的研究、教育和推广机会相对应。UOG/UHCC伙伴关系确实对UOG和关岛领土产生了变革作用，如UOG的承诺函所述，其中包括在UOG建立一个癌症研究中心，并实施了显著提高烟草制品税的立法。在UHCC， U54导致太平洋岛民癌症健康差异研究的增加。在这次U54更新申请中，我们的首要目标是建立我们的伙伴关系，作为促进太平洋岛民癌症健康公平的国家和国际领导者。为了实现这一目标，我们将在过去五年半的成功基础上继续努力。我们申请的各个组成部分的所有具体目标都支持我们的总体目标，即1)通过研究者发起的资金和同行评审的出版物增加UOG教师的数量，继续发展UOG教师的癌症研究能力和竞争力；2)进一步发展UHCC对癌症健康差异的研究重点，特别强调太平洋岛民以及与区域相关的相关主题，如槟榔咀嚼和宫颈癌筛查和预防；3)继续提高UOG和UHCC服务的多民族社区对癌症和癌症预防的认识，重点是太平洋岛民；4)通过继续我们在癌症相关领域为太平洋登陆学生提供成功的硕士、硕士和博士培训项目，并为早期的教师研究人员提供指导，增加美国太平洋登陆者癌症和生物医学科学研究人员的数量。UOG和UHCC的领导高度致力于这一伙伴关系，他们强有力的支持信和对伙伴关系的重要资源承诺证明了这一点。

DESCRIPTION (provided by applicant) Project Summary/Abstract: Americans of Pacific Islander ancestry is a highly underserved minority with a significant, disparate burden of cancer. In addition, they are also highly underrepresented among cancer researchers and cancer health care professionals. The University of Guam (UOG) and the University of Hawaii Cancer Center (UHCC) have been engaged in a unique and successful partnership over the past twelve years, currently supported by a U54 grant. As the only U54 Partnership addressing cancer health disparities in Pacific Islanders, the UOG/UHCC Partnership is characterized by a significant number of very distinctive aspects and opportunities. In particular, 37% of the Guam population is represented by indigenous Chamorros/part-Chamorros, while 38% are Filipino and Micronesian. The unique ethnic characteristics of this UOG/UHCC Partnership are paralleled by its unique geographic characteristics (the region covered by HI, GU, and U.S. Pacific Territories/jurisdictions), as well as unique regional opportunities for research, education, and outreach. The UOG/UHCC Partnership has indeed been transformational for the UOG and the Territory of Guam as specified in UOG's Letter of Commitment, including the establishment of a Cancer Research Center at UOG and implementation of legislation markedly increasing taxes on tobacco products. At UHCC the U54 has resulted in increased cancer health disparities research in Pacific Islanders. In this U54 renewal application, our overarching goal is to establish our Partner- ship as the national and international leader in advancing cancer health equity in Pacific Islanders. To achieve this goal we will build upon the success of the last five and a half years. All Specific Aims of the individual components of our application support our overall objectives, namely 1) to continue to develop the cancer re- search capability and competitiveness of faculty at UOG by increasing the number of UOG faculty with investigator-initiated funding and peer-reviewed publications; 2) to further develop the focus of UHCC research on cancer health disparities, with particular emphasis on Pacific Islanders and related topics of regional relevance such as betel nut chewing and cervical cancer screening and prevention; 3) To continue raising the awareness of cancer and cancer prevention in the multiethnic communities served by UOG and UHCC, with emphasis on Pacific Islanders; and 4) to increase the number of cancer and biomedical science researchers of Pacific Is- lander ancestry in the U.S. by continuing our successful MA, MS, and PhD training programs for Pacific Is- lander students in cancer-related fields, as well as providing guidance to early stage faculty investigators. The leadership at UOG and UHCC are highly committed to this Partnership as evidenced by their strong Letters of Support and the commitment of significant resources to the Partnership.