Pilot Project Core

试点项目核心摘要 酒精研究和教育本土中心（NCARE）的目标是培养创新研究 关于美国印第安人和阿拉斯加原住民（AI/AN）因酒精使用障碍（AUD）而造成的健康不平等， 包括其预防、诊断、治疗和整个生命周期的后果。一个关键的战略， 实现这一目标的方法是为试点项目提供资金，这些项目将开发新的方法来改善AI/AN人口 健康试点项目提供了一种方法来种子新兴的研究领域，探索新的方法，并追求 新的区域和国家合作，可以发展成为独立资助的研究或示范 项目现有的以大学为基础的试点供资办法提供的资金有限（例如，5,000 - 10,000美元）， 通常不足以进行以社区为基础的研究，通常仅限于家庭调查 机构。NCARE的核心试点项目旨在确定和分配大量资金，以支持 试点项目，严格测试的做法，治疗，教育工作，和政策，可以影响持续， 由于AUD，AI/AN健康差异普遍减少。我们会招募一大批调查员 来自NCARE和外部机构，他们可以在试点项目的支持下开始或扩大他们的研究 核心鉴于对美国国立卫生研究院资助的科学劳动力老龄化的严重关切， 健康，以及同样令人担忧的少数民族首席研究员的缺乏，我们将鼓励来自 初级教师和AI/AN调查员。试点项目核心将提供无数的研究可能性，包括 但不限于AUD的病因学、生物学、遗传学、诊断、治疗和预防的研究， 其生物医学、心理社会和经济后果。我们的具体目标是：（1）创建一个试点项目 核心资助创新试点项目，对澳大利亚的澳元和相关的卫生不公平现象有意义的影响， AI/AN社区; 2）将科学审查过程作为初级研究人员的学习机会， 希望获得审查经验的NCARE成员;以及3）开发集中的研究服务， 领导NCARE试点项目的调查人员，包括对酒精有浓厚兴趣的初级调查人员 research.我们还将利用我们在其他小额赠款项目中的成功经验， 后勤和科学资源，以研究人员的建议符合我们的严格标准。通过创建一个 集中的研究支持服务，并为NCARE试点项目分配大量的财政资源，这 这种方法将促进创新和严谨研究的生态系统。核心试点项目的活动 将支持全国范围内的研究人员，从而促进新的科学方法的发展， 技术和方法相关的创新，目标导向的AUD研究在全国范围内。

PILOT PROJECT CORE ABSTRACT The goal of the Native Center for Alcohol Research and Education (NCARE) is to nurture innovative research on health inequities among American Indians and Alaska Natives (AI/ANs) due to alcohol use disorders (AUDs), including their prevention, diagnosis, treatment, and consequences across the lifespan. One critical strategy for achieving this goal is to fund pilot projects that will develop novel approaches to improving AI/AN population health. Pilot projects provide a way to seed emerging research areas, explore new methodologies, and pursue new regional and national collaborations that could evolve into independently funded research or demonstration projects. Existing university-based options for pilot funding provide limited sums (e.g., $5,000-$10,000) that are often inadequate to conduct community-based research and are typically restricted to investigators at the home institution. The Pilot Project Core of NCARE is designed to identify and allocate substantial funding to support pilot projects that rigorously test practices, treatments, educational efforts, and policies that can effect sustained, widespread reductions in AI/AN health disparities due to AUDs. We will recruit a broad range of investigators from NCARE and outside institutions who can begin or augment their research with support from the Pilot Project Core. Given serious concerns about the aging of the scientific workforce funded by the National Institutes of Health, and the equally worrisome dearth of minority Principal Investigators, we will encourage applications from junior faculty and AI/AN investigators. The Pilot Project Core will offer myriad possibilities for research, including but not limited to studies of the etiology, biology, genetics, diagnosis, treatment, and prevention of AUDs and their biomedical, psychosocial, and economic consequences. Our Specific Aims are to: 1) Create a Pilot Project Core to fund innovative Pilot Projects with meaningful implications for AUDs and related health inequities in AI/AN communities; 2) Use the scientific review process as a learning opportunity for junior investigators and NCARE members who desire reviewing experience; and 3) Develop centralized research services that support the investigators who lead NCARE Pilot Projects, including junior investigators with a strong interest in alcohol research. We will also leverage our successful experience with other small grant programs to offer financial, logistical, and scientific resources to researchers whose proposals meet our rigorous criteria. By creating a centralized research support service and allocating substantial financial resources for NCARE Pilot Projects, this approach will foster an ecosystem of innovative and rigorous research. The activities of the Pilot Project Core will support investigators nationwide, thereby contributing to the development of new scientific methods, technologies, and approaches pertinent to innovative, goal-directed AUD research on a national scale.