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Structural biology of bacterial outer membrane proteins (overall information: 411-445, 456-458) (446)

Structural biology of bacterial outer membrane proteins (overall information: 411-445, 456-458) (446)
细菌外膜蛋白的结构生物学(总体信息:411-445、456-458)(446)
批准号:
9477717
负责人:
SUSAN K. BUCHANAN
金额:
$31.45万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至

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中文摘要
翻译
膜蛋白生产和分析中心(COMPPä)已经选择了15个DBP,这将提供 推动每一项研发工作的动力。我们用这一节来描述DBP 调查人员,他们的基础是 选择,并概述它们与研发与发展的互动关系。详细介绍了15个DBP中的10个;详细 附录中提供了对其他五个项目的说明。每个研发项目的每个目标至少有三个订阅者 DBPS。所选择的DBP代表了该领域普遍公认的具体技术障碍。 我们将通过努力克服这些障碍来完善我们的方法和技术。解决 这些问题将产生结果,而这些结果反过来又开启了新的生物学问题。这些问题将在 反过来,在他们的解决方案中提出新的技术挑战,开始新一轮的技术开发。
英文摘要
The Center on Membrane Protein Production and Analysis (COMPPÅ) has chosen 15 DBPs, which will provide a driving force for each of the TR&Ds. We use this section to describe the DBP investigators, the basis of their selection, and outline their interaction with TR&Ds. Ten of the 15 DBPs are presented in detail; detailed descriptions for the five others are provided in the Appendix. Each Aim of each TR&D has at least three subscribed DBPs. DBPs chosen represent specific technological roadblocks that are generally acknowledged in the field. We will refine our methodologies and technologies by working towards surpassing these roadblocks. Solving these problems will produce results that, in turn, open up new biological questions. These questions will, in turn, pose new technical challenges in their solution, starting a new round of technology development.
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