Optimizing a dyadic physical activity intervention for Hispanics with osteoarthritis and their physical activity supporter

项目摘要/摘要 拉美裔美国人不太可能达到体力活动指南，而患有骨关节炎的人更有可能报告 比非西班牙裔白人更大的关节疼痛、功能限制和工作限制。在拉美裔美国人中，社交 文化因素是重要的干预考虑因素，因为重视相互依存 在西班牙传统文化中的独立性。据推测，对文化敏感的PA干预 专为拉美裔设计，有可能减少体力活动的差异，从而减少骨性关节炎症状。这 这项研究将使自我管理的6周步行干预适用于患有骨关节炎、卡米诺综合征的西班牙裔患者 Gusto(轻松行走)由患有骨关节炎的西班牙裔人和他们的社交网络成员组成的二人组 世卫组织支持他们的体力活动尝试(“支持者”)。发展二元性体力活动干预 由相互依赖的文化价值观塑造的将吸引患有骨关节炎的拉美裔人及其支持者 同样，从而积极地影响彼此的体力活动，并提供更多的骨关节炎症状 如释重负。两个目标将实现拟议研究的总体目标：1)开发四个候选二元 针对PA和OA症状的组件；以及2)使用 试点前后的随机研究。在第一个目标下，将开发四个二元干预组件，包括 来自利益相关者小组的输入和来自指导团队的指导。五个干预条件将是 测试实施的可接受性和可行性(N=每个条件10个二元组)。四个条件将包括 候选组件之一+Camine conn Gusto，第五个条件将包括所有候选组件 组份+卡米明康斯托。基于定性和定量评估以及利益相关者小组 反馈，将对四个二元干预组成部分进行修订，为目标2做准备。 目的：采用随机化析因设计来确定二元干预的初始效果 西班牙裔骨性关节炎患者日常生活中所需的成分。析因设计将试行测试条件 由不同的成分组合组成，当添加到Camine cons Gusto中时，以展示最初的 在六个星期内每天循序渐进的效果。这一目标也将允许检查相互影响。 在患有骨性关节炎的西班牙裔人和他们的身体活动支持者之间使用 并元分析(行为者-伙伴相互依赖模型)。拟议的研究将解决以下几个限制 A)侧重于患有骨关节炎的西班牙裔人，以及b)检查一系列二元组 以确定应在将来的试验中保留的那些组件。调查结果将 通过未来的R01通知随机对照试验，以评估优化的二元干预的疗效 仅包含“活动”组件的包。

PROJECT SUMMARY/ABSTRACT Hispanics are less likely to meet physical activity guidelines and those with osteoarthritis are more likely to report greater joint pain, functional limitations, and work limitations than non-Hispanic Whites. Among Hispanics, social and cultural factors are important intervention considerations because of the value placed on interdependence over independence in traditional Hispanic culture. It is hypothesized that culturally sensitive PA interventions designed for Hispanics offer potential to reduce disparities in physical activity and therefore OA symptoms. This study will adapt the self-administered 6-week walking intervention for Hispanics with osteoarthritis, Camine con Gusto (Walk with Ease) for dyads consisting of Hispanics with osteoarthritis and a member of their social network who supports their physical activity attempts (“supporter”). Developing a dyadic physical activity intervention shaped by the cultural value of interdependence will engage Hispanics with osteoarthritis and their supporters equally, thus positively influencing each other’s physical activity and providing greater osteoarthritis symptom relief. Two aims will achieve the overall goals of the proposed study: 1) Develop four candidate dyadic components targeting PA and OA symptoms; and 2) Determine the initial efficacy of the components using a randomized pre-post pilot study. Under the first aim, four dyadic intervention components will be developed with the input from a stakeholder panel and guidance from the mentoring team. Five intervention conditions will be tested for acceptability and feasibility of implementation (N= 10 dyads per condition). Four conditions will include one of the candidate components + Camine con Gusto and the fifth condition will include all candidate components + Camine con Gusto. Based on qualitative and quantitative assessments and stakeholder panel feedback, the four dyadic intervention components will be revised in preparation for Aim 2. Under the second aim, a randomized factorial design will be implemented to determine the initial efficacy of the dyadic intervention components on the daily steps of Hispanics with osteoarthritis. The factorial design will pilot test conditions consisting of different combinations of the components that when added to Camine con Gusto demonstrate initial efficacy in daily steps over six weeks. This aim will also allow for the examination of the reciprocating influences between Hispanics with osteoarthritis and their physical activity supporters on each other’s daily steps using dyadic analysis (actor-partner interdependence model). The proposed study will address several limitations of previous interventions by a) focusing on Hispanics with osteoarthritis, and b) examining an array of dyadic components separately to determine those components that should be retained in a future trial. Findings will inform a randomized controlled trial via a future R01 to evaluate the efficacy of the optimized dyadic intervention package containing only “active” components.