Echoic Memory Function and Physiology in the Rhesus Macaque
Echoic Memory Function and Physiology in the Rhesus Macaque
批准号:
10382304
负责人:
Tobias Teichert
金额:
$39.13万
依托单位国家:
美国
项目类别:
财政年份:
2019
资助国家:
美国
项目状态:
已结题
起止时间:
2019-06-01 至 2024-03-31
关键词:
Active ListeningAffectAnimalsAuditoryAuditory areaBehavioralBenchmarkingCategoriesCharacteristicsDataDiscriminationDissectionElectrodesElectrophysiology (science)ExhibitsEyeGlutamatesHomologous GeneImpairmentIndividualInterventionKetamineLeadLinkMacacaMacaca mulattaMeasuresMemoryMemory impairmentMidazolamModelingMolecularMonkeysNeuronsPerformancePharmacologyPhysiologyPitch DiscriminationPositioning AttributePrimatesProcessPropertyPupilRandomizedReadingRefractorySchizophreniaShort-Term MemoryStimulusSynapsesTestingTimeWeightWorkauditory processingawakebehavior measurementencephalographyimprovedmemory encodingneural correlatenonhuman primatenovelpreventpsychosocialrelating to nervous systemresponseshared memorysocial cognitionsoundsynaptic depressiontherapy development
中文摘要
7.项目总结
背景资料。回声记忆(Echic Memory,EM)是一种前范畴被动的听觉短时记忆。
EM对于处理本质上转瞬即逝但仅在与他人的关系中获得意义的声音是必不可少的
听起来。回声记忆的神经底物尚未确定。公认的是,
声音的处理会暂时降低听觉皮质对相似声音的反应
(不稳定或刺激特异性适应:R/SSA)。已经注意到,R/SSA以相似的时间衰落-
常量,因为有关过去声音的信息从EM中消失。这项拟议的工作将检验这样一个假设,即
R/SSA反应性降低的原因是EM的神经底物。
英文摘要
7. PROJECT SUMMARY
Background. Echoic memory (EM) is a pre-categorical and passive form of auditory short-term memory.
EM is essential for processing sounds that are inherently fleeting yet acquire meaning only in relation other
sounds. The neural substrate of echoic memory has not bee identified. It is well-established that the
processing of a sound temporarily reduces the responsiveness of auditory cortex to similar sounds
(refractoriness or stimulus-specific adaptation: R/SSA). It has been noted that R/SSA fade with similar time-
constants as information about past sounds fades from EM. The proposed work will test the hypothesis that the
cause for the reduced responsiveness that underlies R/SSA is the neural substrate of EM.
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会议论文
Echoic Memory Function and Physiology in the Rhesus Macaque
-
批准号:9796862
-
项目类别:
-
资助金额:$39.13万
-
财政年份:2019
-
负责人:Tobias Teichert
-
依托单位:
Echoic Memory Function and Physiology in the Rhesus Macaque
-
批准号:10599096
-
项目类别:
-
资助金额:$39.13万
-
财政年份:2019
-
负责人:Tobias Teichert
-
依托单位:
Neural networks of auditory refractoriness and mismatch generation in the rhesus macaque
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批准号:9295151
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项目类别:
-
资助金额:$19.06万
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财政年份:2017
-
负责人:Tobias Teichert
-
依托单位:
海外基金