Indiana University (IU) Clinical Center for Chronic Pancreatitis Clinical Research Network

慢性胰腺炎(CP)是一种进行性疾病，常导致外分泌和内分泌功能丧失和 使人虚弱的腹痛；尚不清楚为什么有些人会进展并出现并发症，包括 胰源性糖尿病(T3cDM)和/或胰腺癌(PDAC)。在慢性精神疾病研究联盟 研究人员提出，最初于2015年成立的胰腺炎、糖尿病和胰腺癌(CPDPC) 并启动了几项关于风险因素、环境影响和概念验证研究的强有力的研究 推动这一领域向前发展，特别是那些增加T3cDM和PDAC风险的因素。在第二个 在国家方案政治部的周期内，这一行政补编将允许持续征聘和保留科目 在国家发改委的两项高度优先的纵向研究中，即继续和INSPPIRE 2，以及 检测，旨在更好地定义和表征T3cDM。

Chronic pancreatitis (CP) is a progressive disease, often leading to loss of exocrine and endocrine function and debilitating abdominal pain; it is unknown why some individuals progress and develop complications, including pancreatogenic diabetes (T3cDM) and/or pancreas cancer (PDAC). In the Consortium for the study of Chronic Pancreatitis, Diabetes and Pancreatic Cancer (CPDPC), initially formed in 2015, investigators have proposed and initiated several well-powered studies of risk factors, environmental influences, and proof-of-concept studies to move the field forward, particularly those factors that increase the risk of T3cDM and PDAC. In the second cycle of the CPDPC, this administrative supplement will allow for ongoing recruitment and retention of subjects in two of the CPDPC's high-priority longitudinal studies, namely PROCEED and INSPPIRE 2, as well as DETECT, designed to better define and characterize T3cDM.