UTMB OAIC Biostatistics and Data Management Resource Core 3 (BDMRC3)

项目摘要/摘要(BDMRC3) UTMB OAIC生物统计和数据管理资源核心3(BDMRC3)提供生物统计 支持、协作和培训，并为研究开发新的生物统计和数据管理工具 与UTMB OAIC主题相关，该主题是将功能丧失和获得的途径转化为干预措施 优化不同老年人群的功能恢复。作为OAIC新资源建立以来 2014年，BDMRC3与OAIC调查人员迅速建立了牢固的工作关系，并 支持6名学者、17个伊斯兰会议组织试点/发展项目、6个NIH R和K补助金、3个T32、1个F30、2个 AHRQ的巨额拨款，以及德克萨斯州CPRIT中心的拨款。它已经出版了54份出版物。 BDMRC3的具体目标是： 1.作为OAIC项目的调查人员协作，专注于改善身体功能和恢复 上了年纪的人。这些项目包括试验性研究、发展项目和外部资助的研究； 2.培训研究教育核心(REC)的生物统计学和数据管理方面的学者，以帮助他们 计划、实施和解释他们在老龄化方面的调查结果； 3.加强科研信息系统基础设施，协助采购、管理和 处理从现有数据库收集的数据； 4.为老龄化研究开发新的生物统计学方法和可视化分析应用程序。 BCMRC3对UTMB OAIC的意义与四项主要任务有关。1)数据扩容 基础设施，以整合和协调跨OAIC项目和数据源的测量，增强 在使用多个OAIC项目的电子健康记录数据方面的可访问性，并与 UTMB RCMAR和UTMB P2C；2)BCMRC3人员共同作为设计的关键资源运行， 在OAIC项目中进行分析和解释；3)BCMRC3教师指导REC学者，导致长期 合作和更有效的研究开发；以及4)BCMRC3成员开发和改编小说 改进OAIC研究结果的有效性和实用性的分析方法。

PROJECT SUMMARY/ABSTRACT (BDMRC3) The UTMB OAIC Biostatistics and Data Management Resource Core 3 (BDMRC3) provides biostatistical support, collaboration and training, and develops novel biostatistic and data management tools for research relevant to the UTMB OAIC theme which is Translate pathways of functional loss and gain into interventions to optimize functional recovery in diverse geriatric populations. Since its establishment as a new OAIC Resource Core in 2014, the BDMRC3 has rapidly developed strong working relationships with OAIC investigators, and supported six Scholars, 17 OAIC pilot/developmental projects, six NIH R and K grants, three T32, one F30, two large AHRQ grants, and a Texas CPRIT center grant. It has produced 54 publications. Specific aims of the BDMRC3 are: 1. Collaborate as investigators for OAIC projects with focus on improving physical function and recovery in older adults. The projects include pilot studies, developmental projects, and externally funded research; 2. Train Research Education Core (REC) scholars in biostatistics and data management to help them plan, conduct, and interpret results of their investigations in aging; 3. Enhance research information system infrastructure to assist in the procurement, management, and processing of data collected from extant databases; 4. Develop novel biostatistics methods and visual analytic applications for aging research. The significance of BCMRC3 for the UTMB OAIC is related to four main tasks. 1) Expanding the data infrastructure to consolidate and harmonize measurements across OAIC projects and data sources, enhance accessibility in the use of EHR data for multiple OAIC projects, and share available sources of data with the UTMB RCMAR and UTMB P2C; 2) BCMRC3 personnel collectively operates as a key resource for design, analysis, and interpretation in OAIC projects; 3) BCMRC3 faculty mentors REC scholars, leading to long-term collaborations and more effective research development; and 4) BCMRC3 members develop and adapt novel analytical methods to improve the validity and utility of results stemming from OAIC research.