CORALE-SeroNet Admin Core

行政核心摘要 行政核心将提供一个集中、协调的基础设施， 评估和促进CORALE-SeroNet U 54计划总体科学目标的进展。 由项目主任（Susan Cheng博士、Jane Figueiredo博士和Michael Karin博士）领导的核心将进行互动 与内部和外部咨询委员会和社区咨询委员会，并将提供定期 对方案举措和实现以下目标的进展情况的反馈。一是提供 领导，以确保整体计划的生产力和整个SeroNET联盟的有效协作。 行政核心将提供：（a）集中和有效的行政支助， CORALE-U 54活动和整个SeroNet联合体的所有协作努力;（B）定期监测和 评估所有项目活动，并为内部和外部利益攸关方编写报告， 评估基础研究和临床研究之间的转化机会以及最有效的分配 （c）与咨询委员会和外部组织，包括其他SeroNet 中心和外部调查人员关于实现SeroNet总体目标的进展情况以及 加强或整合科学和培训活动;（d）提供财政行政支助， 适当管理预算和财政资源;（e）支持确保研究合规， 所有研究方案的完整性;以及（f）数据和成果传播的行政协调， 包括数据共享和公布所有研究结果。特别是，领导行政核心 有一个积极的沟通计划和资源，以传播我们正在进行的研究结果，以更广泛的临床， 研究和社区。第二，行政核心将提供组织结构， 资源核心的管理支持。行政核心将提供一个高效和集中的 支持两个核心的所有活动的行政结构：（a）招募和生物库核心， 和（B）免疫生物分析核心（IBC）。第三。行政核心将提供组织 在SeroNet内外进行协作。我们的愿景是开发和管理一个 一项研究计划，将整合我们的人口，临床，转化和基础科学科学家团队 和独特的患者资源与更广泛的科学界领导的SeroNET，以满足迫切需要， 了解潜在的机制和潜在的治疗方法，以解决关键的知识差距 关于SARS-CoV-2的易感性和免疫潜力。

ABSTRACT for Administrative Core The Administrative Core will provide a centralized, coordinated infrastructure for effectively supporting, evaluating, and stimulating progress towards the overall scientific goals of the CORALE-SeroNet U54 Program. The Core led by the Program Directors (Drs. Susan Cheng, Jane Figueiredo, and Michael Karin) will interact with Internal and External Advisory Committees and a Community Advisory Board and will provide regular feedback on programmatic initiatives and progress toward achieving the following goals. First, to provide leadership to ensure overall program productivity and effective collaboration across the SeroNET consortium. The Administrative Core will provide: (a) centralized and efficient administrative support and coordination of all CORALE-U54 activities and all collaborative efforts across the SeroNet consortium; (b) regular monitoring and evaluation of all project activities and generation of reports for internal and external stakeholders including assessments of opportunities for translation between basic and clinical research and the most effective allocation of resources; (c) engagement with advisory committees and external organizations, including other SeroNet centers and external investigators regarding progress toward the overall goals of SeroNet and opportunities for augmenting or integrating scientific and training activities; (d) financial administrative support to ensure appropriate management of budgets and financial resources; (e) support to ensure research compliance and integrity of all research programs; and, (f) administrative coordination for the dissemination of data and results, including data sharing and publication of all research findings. In particular, the Leadership Administrative Core has an active communication plan and resources for disseminating our ongoing findings to the broader clinical, research and lay communities. Second, the Administrative core will provide organizational structure and management support for the Resource Cores. The Administrative Core will provide an efficient and centralized administrative structure to support all activities of the two Cores: (a) Recruitment and Biobanking Core (RBC), and (b) the Immune Bioanalytics Core (IBC). Thirdly. The Administrative Core will provide organizational structure and management to collaborate within SeroNet and beyond. Our vision is to develop and manage a research program that will integrate our team of population, clinical, translational, and basic science scientists and unique patients resources with the broader scientific community led by SeroNET to meet the urgent need to understand the underlying mechanisms and potential therapeutic approaches to address key knowledge gaps regarding SARS-CoV-2 susceptibility and potential for immunity.