Research Training Program in Cardiovascular Surgery

这是欣欣向荣的心血管领域T32研究培训计划的首次竞争性续签申请 手术。心血管疾病及其并发症是美国死亡和残疾的主要原因 各州。外科心血管疾病对健康的影响促使人们强烈需要确保持续的 通过培训该领域未来的调查人员进行研究。不幸的是，心脏和血管外科的毕业生 培训项目面临着建立研究职业生涯的严峻挑战。利用我们在中国的地位 得克萨斯医疗中心，世界上最大的医疗综合体，我们的博士后培训项目- 血管外科研究旨在：(1)增加进入心血管领域的医学博士和博士群体 外科研究职业，以及(2)为我们的受训人员提供成功和多产所必需的技能 在心血管研究方面。我们每年招收两名实习生(MD外科实习医生、其他临床医生或博士) 分成三个培训轨道，每个为期两年：生物工程和生物设计，基础和翻译再培训 搜索、数据科学和卫生服务研究。学员可以进行不同的研究职业培训 然而，在所有情况下，重点都是解决与心血管外科医生相关的临床问题。 为了提供一系列的培训机会和指导，我们从贝勒学院招募了22名导师 莱斯大学和休斯顿大学。在三条训练赛道中，这22名男子- 根据他们的专业知识和现有的合作关系，ToR被分成特定的主题，如主动脉疾病- 积极主动的关系。每个途径都允许学员选择完成一个学位，例如 生物信息学；[所有课程都包括必修的助学金写作课程。]我们的项目主管是托德·罗森加特， 医学博士，BCM迈克尔·E·德巴基外科主任；联席董事是斯科特·勒梅尔，医学博士，副 和芭芭拉·特劳特纳，医学博士，临床和卫生服务研究主任。我们的 领导力得到了执行指导委员会的支持，这是一个由11名当地研究专家组成的多元化小组 教育和指导。计划领导还由一个外部咨询委员会指导，该委员会由 五名科学家，他们都曾指导和/或担任过T32培训计划的导师。在过去五年中 在申请的几年里，我们收到了来自美国各地的91个关于该项目的查询，导致10个 参加该项目的实习生中，有三人来自休斯顿郊外的外科住院医师项目。我们的 通过支持在科学工作中代表性不足的群体的国家专业组织进行外联-- 武力卓有成效；[我们接受的申请者中有36%来自生物医学SCI中代表性不足的群体- 感觉到了。我们的三名博士毕业生都获得了一个学术研究职位；我们的三名医学博士毕业生回来了 去参加临床培训。我们的学员和他们的导师以及三位学员一起出版了手稿 获得外部资金。]我们期待着我们的计划有机会继续扩大我们的 高素质的医学博士和博士，为心血管外科研究领域的高影响力做出贡献。

This is a first competitive renewal application for a thriving T32 Research Training Program in Cardiovascular Surgery. Cardiovascular diseases and their complications are leading causes of death and disability in the United States. The health implications of surgical cardiovascular disease create a strong need to ensure sustained research by training future investigators in the field. Unfortunately, graduates of cardiac and vascular surgery training programs face steep challenges to establishing research careers. Taking advantage of our position in the Texas Medical Center, the largest medical complex in the world, our postdoctoral training program in cardi- ovascular surgical research is designed to: (1) increase the pool of MDs and PhDs who enter cardiovascular surgical research careers, and (2) provide our trainees with the skills necessary to be successful and productive in cardiovascular research. We accept two trainees per year (MD surgery residents, other clinicians, or PhDs) into three training tracks, each two years in duration: bioengineering and biodesign, basic and translational re- search, and data science and health services research. Trainees can pursue diverse research career training opportunities, yet in all cases the focus is on addressing a clinical problem relevant to cardiovascular surgeons. To provide a range of training opportunities and mentorship, we have recruited 22 mentors from Baylor College of Medicine (BCM), Rice University, and the University of Houston. Within the three training tracks, the 22 men- tors are grouped into specific themes, such as “aortic disease,” based on their expertise and existing collabora- tive relationships. Each track allows trainees the option of completing a degree, such as a Master’s Degree in Bioinformatics; [all tracks include a mandatory Grant Writing course.] Our Program Director is Todd Rosengart, MD, Chair of the Michael E. DeBakey Department of Surgery at BCM; Co-Directors are Scott LeMaire, MD, Vice Chair for Research, and Barbara Trautner, MD, PhD, Director of Clinical and Health Services Research. Our leadership is supported by an Executive Steering Committee, a diverse panel of 11 local experts in research education and mentoring. Program leadership is also guided by an External Advisory Committee composed of five scientists who have all directed and/or served as a mentor in T32 training programs. Over the past five application years, we received 91 inquiries about the program from across the United States, leading to 10 trainees entering the program, three of whom were from surgical residency programs outside Houston. Our outreach through national professional organizations that support groups underrepresented in the scientific work- force has been fruitful; [36% of our accepted applicants are from a group underrepresented in biomedical sci- ences. Our three PhD graduates all secured an academic research position; our three MD graduates returned to clinical training. Collectively our trainees have published 64 manuscripts with their mentors, and three trainees secured external funding.] We look forward to the opportunity for our program to continue to grow the pool of highly qualified MDs and PhDs contributing to the high-impact arena of research in cardiovascular surgery.