Growing Data-science Research in Africa to Stimulate Progress (GRASP)

摘要 非洲不断增长的数据科学研究以推动进步(GRAP) 为解决非洲日益加重的非传染性疾病负担所作的努力 由于可持续和本土研究能力的巨大不足而严重受损 充分合格的人员对于阐述个性化的、针对具体情况的干预措施至关重要 非洲人口。神经系统疾病是导致死亡和残疾的主要非传染性疾病原因。脑区 健康决定了大脑资本，是实现全面健康和所有可持续发展的核心 发展目标。然而，目前的DS-I非洲方案没有专门的培训 脑健康研究计划，以揭示其决定因素，特别是社会人口和生活方式 在其他地方发挥重要作用的因素。 GRAPP的目标是建立一个可持续发展的科学家队列，以应对大脑健康负担 通过提高精选的非洲学者的数据科学技能来解开社会人口 影响大脑健康和心血管风险的决定因素和饮食和生活方式因素 H3非洲和DS-I非洲联盟的警报器、RISE、主席和其他相关数据集 更远一点。这将包括将社会人口数据与认知、神经成像、 基因组学，气候和地理数据，指导研究项目和财团相关 在一个由五名选定的受训研究人员及其精英导师组成的多学科团队中开展活动 每年一次，连续三年。 掌握将增加学者的科学知识、专业技能、动力和 翻译数据科学研究领域的证书，特别关注大脑健康 重点是确定社会人口决定因素和其他标志和模式 来自基因组学、脑成像、地理信息系统(GIS)地图和公共数据 健康数据。该培训包括为期9个月的研究生证书课程，该课程将包括 六(6)个月的在线培训活动和六(6)周的强制性强化实习 尼日利亚伊巴丹大学(UI)和一个研究项目。指导将通过Mentor得到加强 匹配(内容和分析领域)和同行指导网络。研究生阶段的每位学者 证书课程将分配给一名导师/主管(最好是 培训或主办机构和辅导将在线或面对面进行， 导师/被辅导者偏好)。GRASH的有效性将以学者为基础进行监测 学术职位和出版物；为研究人员发起的研究项目或 职业发展奖。 1

ABSTRACT Growing Data-science Research in Africa to Stimulate Progress (GRASP) Efforts to address the increasing burden of non-communicable diseases (NCDs) in Africa have been hugely impaired by the vast deficit of sustainable & indigenous research capacities & adequately qualified personnel vital for articulating personalized, context-specific interventions for African populations. Neurological disorders are a leading NCD cause of death and disability. Brain health, which determines brain capital, is central to achieving overall health and all sustainable development goals. However, the current DS-I Africa programs do not have a dedicated training program in brain health research to unravel its determinants, especially sociodemographic and lifestyle factors which play a major role elsewhere. GRASP is aimed at developing a sustainable cohort of scientists to tackle the brain health burden by improving the data science skill of selected African scholars to unravel sociodemographic determinants and dietary & lifestyle factors affecting brain health & cardiovascular risk using the SIREN, ARISES, CHAIR, & other relevant datasets in H3Africa & DS-I Africa consortia and beyond. This will include integrating sociodemographic data with cognitive, neuroimaging, genomics, climate & geographical data, in mentored research projects & consortia-related activities in a multidisciplinary team of five selected researchers-in-training & their elite mentors annually for three years. GRASP will increase the scholars' scientific knowledge, professional skills, motivation, & credentials in the field of translational data science research with a specific focus on Brain health with emphasis on identifying sociodemographic determinants and other markers and patterns in data from genomics, brain imaging, Geographic Information System (GIS) mapping & public health data. The training comprises a 9-month Postgraduate Certificate program that will include six (6) months of online training activities & a compulsory six (6) weeks intensive residency at the University of Ibadan (UI), Nigeria and a research project. Mentoring will be enhanced via mentor matching (content & analytic area) & peer mentoring networks. Each scholar in the Postgraduate Certificate program will be assigned to a mentor/supervisor (preferably a faculty member of the training or host institutions & mentoring will take place online or face-to-face based on the mentor/mentee preference).The effectiveness of GRASP will be monitored based on Scholar academic positions & publications; and funding for investigator-initiated research projects or career development awards. 1