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中文摘要
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项目摘要/摘要--核心A 《肝细胞癌卵细胞孢子管理核心》(核心A)由孢子PIs Ronald Buckanovich,MD, 博士和罗伯特·爱德华兹医学博士。核心A将(I)提供科学、财政和一般行政监督 所有孢子组成部分,(Ii)努力促进三个孢子项目的研究生产力,(Iii) 扩大孢子的两个共享资源核心的效用和效率,以及(Iv)确保成功 职业提升计划(CEP)和发展研究计划(DRP),以生成渠道 新的OVCA调查人员和项目。为了确保孢子的成功,核心A将协调共享 孢子数据以及内部和外部通信和互动。这包括协调 与合作机构达成协议,并与患者权益倡导者进行社区宣传。核心A将召开 所有孢子调查人员参加每月会议,协调定期的行政和科学 审核、发放和宣传RFA,并安排对收到的CEP和DRP申请进行审查;以及 与NCI翻译研究项目办公室密切合作。它将提供管理框架 通过它,孢子执行委员会、内部咨询委员会(IAB)和外部咨询委员会 (EAB)可以评估计划活动,并将根据需要重新分配资源,以最大限度地取得进展 孢子的翻译目标。核心A将监督各个孢子、CEP和DRP的预算 确保孢子和机构共享之间不发生重复工作的项目和核心 资源,国家财团或合作团体,或其他资助的研究赠款。核心还将 确保孢子的研究活动符合所有地方和联邦法规 和指南,包括保护患者安全和个人健康信息的指南。核心A将 受益于协助安排日程和准备报告的合格孢子管理员的工作 和手稿。 影响:通过核心A功能,孢子作为一个整体将受益于基本要素的集中 服务,每个孢子组成部分将有机会最大限度地致力于 卵巢癌的研究和以患者为中心的进展。
英文摘要
PROJECT SUMMARY/ABSTRACT – CORE A The HCC OvCa SPORE Administrative Core (Core A) is co-directed by SPORE PIs Ronald Buckanovich, MD, PhD and Robert Edwards, MD. Core A will (i) provide scientific, fiscal, and general administrative oversight to all SPORE components, (ii) work to facilitate the research productivity of the three SPORE Projects, (iii) expand the utility and efficiency of the SPORE’s two Shared Resource Cores, and (iv) ensure the success of the Career Enhancement Program (CEP) and Developmental Research Program (DRP) to generate a pipeline of new OvCa investigators and projects. To ensure the success of the SPORE, Core A will coordinate sharing of SPORE data as well as internal and external communications and interactions. This includes coordinating agreements with collaborating institutions and community outreach with patient advocates. Core A will convene monthly meetings attended by all SPORE Investigators, coordinate periodic administrative and scientific reviews, release and publicize RFAs and arrange for the review of received CEP and DRP applications, and work closely with the NCI Translational Research Program Office. It will provide the administrative framework through which the SPORE Executive Committee, Internal Advisory Board (IAB), and External Advisory Board (EAB) can evaluate program activities and will redirect resources, as appropriate, to maximize progress toward the SPORE’s translational goals. Core A will monitor the budgets of the individual SPORE, CEP, and DRP Projects and Cores to ensure that no duplication of effort occurs between the SPORE and institutional shared resources, national consortia or cooperative groups, or other funded research grants. The Core will also ensure that the SPORE’s research activities are conducted in compliance with all local and federal regulations and guidelines, including those for protecting the safety and personal health information of patients. Core A will benefit from the effort of a qualified SPORE Administrator who assists in scheduling and in preparing reports and manuscripts. Impact: Through Core A functions, the SPORE as a whole will benefit from the centralization of essential services, and each SPORE component will be afforded the opportunity to maximize the effort devoted to research and patient-oriented advances in ovarian cancer.
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HCC Ovarian Cancer SPORE
Defining the impact of stromal aging on ovarian cancer initiation
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