NIA Core Center to Build Neurodegenerative Disease Research Faculty At Penn

描述(由申请人提供)：宾夕法尼亚大学(宾夕法尼亚大学)拥有强大的跨学科研究项目，研究与衰老相关的神经退行性疾病，发展对与衰老相关的神经退行性疾病的基本见解，并实施制定策略以预防或改善阿尔茨海默氏症(AD)和帕金森病(PD)、肌萎缩侧索硬化症(ALS)和前颞叶变性(FTLD)的计划。P30神经退行性疾病核心中心将通过招聘两名新教师来进一步建立宾夕法尼亚大学神经退行性疾病研究人员的多学科社区，他们的专业知识与现有项目相辅相成，同时为这些项目增加新的内容。这包括在神经退行性疾病基因组研究方面拥有专长的终身制追踪神经学教员，以及在阐明代谢综合征对AD风险增加的贡献方面具有专长的实验神经病理学教员的终身教职追踪。这将通过在全国范围内寻找这些教师以及指导计划和机构支持来实现，以将这些新教师无缝地整合到宾夕法尼亚大学神经退行性疾病研究计划网络中。这将创造新的就业机会，并通过改善对AD、PD、FTLD、ALS和相关疾病患者的护理，提高降低医疗成本的能力。 公共卫生相关性：完成P30神经退行性疾病核心中心的目标将进一步建立宾夕法尼亚大学神经退行性疾病研究人员的多学科社区，方法是招聘两名新的教职员工，他们的专业知识补充了宾夕法尼亚大学现有的项目，同时为这些项目增加了新的内容。这将创造新的就业机会，并通过改善对阿尔茨海默氏症和帕金森氏病、肌萎缩侧索硬化症和额颞叶变性等与衰老相关的神经退行性疾病患者的护理，从而提高降低医疗成本的能力，从而刺激经济增长。

DESCRIPTION (provided by applicant): The University of Pennsylvania (PENN) has strong interdisciplinary research programs on aging related neurodegenerative disorders that develop basic insights Into aging related neurodegenerative disease and Implement programs for developing strategies to prevent or ameliorate Alzheimer's (AD) and Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), and front temporal lobar degeneration (FTLD). This P30 Neurodegenerative Disease Core Center will build further the multidisciplinary community of neurodegenerative disease researchers at PENN by recruiting two new faculty whose expertise complements existing programs while adding new content to these programs. This includes a tenure track Neurology faculty with expertise In genomic studies of neurodegenerative diseases and a tenure track experimental Neuropathology faculty with expertise in elucidating contributions of the metabolic syndrome to Increased risk for AD. This will be accomplished through a national search for these faculty as well as mentoring programs and institutional support to seamlessly integrate these new faculty into the PENN neurodegenerative disease research program network. This will lead to new job creation and enhanced capacity to reduce health care costs by improving the care of patients with AD, PD, FTLD, ALS and related disorders. PUBLIC HEALTH RELEVANCE: Completing the Aims of this P30 Neurodegenerative Disease Core Center will build further the multidisciplinary community of neurodegenerative disease researchers at PENN by recruiting two new faculty members whose expertise complements existing PENN programs while adding new content to these programs. This will lead to new job creation and enhanced capacity to reduce health care costs by improving the care of patients with aging related neurodegenerative disorders such as Alzheimer's and Parkinson's disease, amyotrophic lateral sclerosis, and frontotemporal lobar degeneration thereby stimulating economic growth.