Research Education Component (REC)

研究教育部分(REC)的目标是发展基础设施，并提供指导和试点资金 来自NIH和本RFA所描述的医学(UIM)背景的早期职业调查人员 (例如，种族和少数民族、女性、第一代大学生)对开发、测试 以及根据修订的NIH，对少数族裔ADRD患者、护理伙伴和双亲实施行为干预 阶段模型、行为改变科学、国立卫生研究院健康差异研究框架和疾病中心 预防和国家医学科学院预防模式。区域选举委员会将与社区联络处密切合作 与马萨诸塞州阿尔茨海默病研究中心(MADRC)和波士顿 大学ADRC(BU-ADRC)REC(两者都主要关注生物标记物)，以允许资源和 知识，包括将新的生物机制转化为行为健康干预目标。区域经济合作委员会将 支持：1)在ADRD和跨学科行为研究方面提供指导；2)在健康差距、少数民族老龄化方面提供指导 和社区参与的研究；3)开发试点研究计划，以支持UIM早期职业调查人员。费率 ADRD的发病率急剧增加，少数族裔负担最重。ADRD的大部分研究都集中在 对疾病生物学的理解，较少关注初级、二级和初级行为健康干预 三级预防。此外，ADRD的负担不仅影响到受影响的人，也影响到他们的非正式护理伙伴。 在这两个社区，迫切需要研究将科学进步转化为行为健康干预 以及医院设置，以减轻少数族裔患者、护理伙伴和父母的ADRD负担。REC将直接解决 利用：马萨诸塞州综合医院(MGH)、波士顿医疗中心的跨学科专业知识 (BMC)、剑桥健康联盟及其附属诊所；哈佛大学和波士顿大学的杰出资源 包括MADRC、BU-ADRC；NIA资助的行为健康ADRD R25；以及许多其他重要的合作者 在波士顿地区。REC还将密切合作，将活动和指导与其他AD/ADRD RCMAR整合在一起。 REC将由Ana-Maria Vranceanu(临床心理学家)共同领导，拥有行为健康、ADRD、健康方面的专业知识 差异和社区参与的研究，以及良好的指导记录，以及Maureen O‘Connor(临床 心理学家)，他在ADRD和神经心理学方面拥有专业知识，并领导BU-ADRC REC。具体目标是：1) 制定和支持UIM调查员的试点项目方案(3个试点/年；每人40,000美元)，以符合 中心；2)支持飞行员获奖者(将被任命为RCMAR科学家)的职业发展 指导方案；3)支持RCMAR科学家在健康差距、ADRD和行为干预方面的指导 遵循NIH阶段模式、NIA健康差距框架以及CDC和NAM预防模式；4)开发 并与目标1、2和3的领导和行政核心协调执行目标1、2和3的评价计划 马萨诸塞州阿尔茨海默病和痴呆症少数民族老龄化行为研究中心(MASS-enVision)。

The aim of the Research Education Component (REC) is to grow infrastructure and provide mentorship and pilot funding to early career investigators from underrepresented in medicine (UiM) backgrounds as delineated by NIH and this RFA (e.g., racial and ethnic minorities, women, first generation college students) who are interested in the developing, testing and implementing behavioral interventions for minority ADRD patients, care partners and dyads, following the revised NIH Stage Model, the Science of Behavior Change, the NIH Health Disparities Research Framework and the Center for Disease Prevention and National Academy of Medicine Prevention models. The REC will work closely with the Community Liaison and Recruitment Core (CLRC) and with the Massachusetts Alzheimer’s Disease Research Center (MADRC) and Boston University ADRC (BU-ADRC) RECs (both focused primarily on biomarkers) to allow for crosspollination of resources and knowledge including translating novel biological mechanisms into behavioral health intervention targets. The REC will support: 1) mentoring in ADRD and interdisciplinary behavioral research; 2) mentoring in health disparities, minority aging and community engaged research; 3) developing of a pilot studies program to support UiM early career investigators. Rates of ADRD are increasing drastically, with the greatest burden among minorities. Much of ADRD research has been focused on understanding the biology of disease, with less focus on behavioral health interventions for primary, secondary and tertiary prevention. Further, the burden of ADRD impacts not only the affected persons but also their informal care partners. There is a critical need for research to translate scientific advances into behavioral health interventions in both community and hospital settings to decrease ADRD burden for minority patients, care partners and dyads. The REC will directly address this need by leveraging: the interdisciplinary expertise at Massachusetts General Hospital (MGH), Boston Medical Center (BMC), Cambridge Health Alliance and affiliated clinics; the outstanding resources of Harvard and Boston University including MADRC, BU-ADRC; a NIA funded behavioral health ADRD R25; and numerous other important collaborators in the Boston area. The REC will also work closely to integrate activities and mentoring with other AD/ADRD RCMARs. The REC will be co-led by Ana-Maria Vranceanu (clinical psychologist) with expertise in behavioral health, ADRD, health disparities and community-engaged research, and a strong track record of mentoring, and Maureen O’Connor (clinical psychologist) who has expertise in ADRD and neuropsychology and leads the BU-ADRC REC. Specific aims are: 1) to develop and support a pilot project program (3 pilots/year; $40,000 each) from UiM investigators that fit the theme of the center; 2) to support the career development of pilot awardees (who will be named RCMAR Scientists) through a rigorous mentoring program; 3) to support mentoring of RCMAR Scientists in health disparities, ADRD and behavioral interventions following the NIH Stage Model, NIA Health Disparities Framework, and CDC and NAM prevention models; 4) to develop and implement an evaluation plan for aims 1, 2 and 3 in coordination with the Leadership and Administrative core of Massachusetts Center for Alzheimer and dEmeNtia behaVIoral reSearch In minOrity agiNg (Mass-ENVISION).