EXERCISE OPTION PERIOD 1

承包商应提供一个集中的、基于网络的信息技术（IT）数据库，该数据库将提供用户友好的界面，用于输入、上传/导入， 搜索、下载/导出和可视化化学结构和生物活性、药理学和毒理学数据，以及软件技术支持。集中数据系统将收集和维护数据，包括但不限于NIH资助的承包商和PI生产的化学类似物的信息（包括化学结构）以及生物活性、药理学和毒理学试验的数据。数据将由LDT成员、PI、CRO、NIH聘请的顾问和NIH工作人员进行审查和分析。

The Contractor shall provide a centralized, web-based, information technology (IT) database that will provide user-friendly interfaces for entering, uploading/importing, searching, downloading/exporting, and visualizing chemical structures and bioactivity, pharmacology, and toxicology data, as well as software technical support. The centralized data system will collect and maintain data which includes, but is not limited to, information on the chemical analogs produced by NIH-funded contractors and PIs (including chemical structures) and data from bioactivity, pharmacology, and toxicology assays. The data will be reviewed and analyzed by members of an LDT, PIs, CROs, NIH-hired consultants, and NIH staff.