University of Kansas Cancer Center Midwest Pre-Clinical Imaging Center

摘要 堪萨斯大学医学中心寻求建立一种最先进的多模式临床前成像 设施是整个校园总体规划过程中的一个关键要素。这个设施在服务于整个 KUMC园区也将是我们癌症中心的重要资产，因为它寻求在 利用尖端的实验成像技术开发和利用小鼠癌症模型。 在过去的一年里，校园总体规划工作的重点是实现更好的 使我们的物理工厂的能力与我们的基础和翻译研究抱负保持一致，同时 同时使我们的住院临床设施在未来得以扩展。 动物成像设施将服务于整个医学中心园区的研究需求，并将 位于新建的校园隔间的屏障内，该隔间将占据 规划中的癌症中心大楼。这一设施将是大学和地区的重要资产，因为我们正在寻求 扩大、现代化和优化临床前转化研究活动的动物模型的使用。 将设施放置在隔膜屏障内将使我们能够减少必要的动物数量 通过各种不同的技术实现系列成像功能，从而实现特定的研究项目 在我们现有的设施下是可能的。目前的子宫内膜已有近50年的历史，已接近其实用价值 寿命，预计将在未来五年内达到产能，无法适应CT或MRI成像， 并占用了对我们的住院医疗设施进行至关重要的扩建所需的土地。作为一名 结果，这次C06的机会是重新思考、重新想象和更新我们的实验动物的理想时机 设施，并确保它们满足21世纪KUMC的需求。拟议中的项目是一个关键的 构成新的隔间并实现新的校园总体规划，并将为租户提供 堪萨斯大学医学中心校区规划中的空壳空间。癌症中心、大学和 卫生系统领导层已将这一建设作为其最高集体优先事项，已投入约1.5亿美元 到目前为止，已通过慈善努力和国会三次筹集资金为联合基金提供资金 定向支出分配。

Abstract The University of Kansas Medical Center seeks to build a state-of-the-art multi-modality pre-clinical imaging facility as a critical element of a campus-wide master planning process. This facility while serving the entire KUMC campus will also be an important asset for our cancer center as it seeks to expand its efforts in developing and utilizing mouse models of cancer by leveraging cutting edge experimental imaging techniques. The campus master planning effort that has taken place over the past year has focused on achieving better alignment of the capabilities of our physical plant with our basic and translational research aspirations, while simultaneously enabling the future expansion of our inpatient clinical facilities. The animal imaging facility will serve the research needs of the entire medical center campus and will be housed within the barrier of a newly constructed campus-wide vivarium that will occupy the first two floors of a planned cancer center building. This facility will be an important asset for the University and region as we seek to expand, modernize and optimize the use of animal models for preclinical translational research activities. Placement of the facility within the vivarium barrier will allow us to reduce the number of animals necessary for specific research projects by enabling serial imaging capability via a wide variety of techniques that are not possible with our current facilities. The current vivarium is approximately 50 years old, is nearing its useful lifespan, is projected to reach capacity within the next five years, cannot accommodate CT or MRI imaging, and occupies land that is needed for a critically important expansion of our inpatient health care facilities. As a result, this C06 opportunity represents an ideal time to rethink, reimagine, and renew our laboratory animal facilities and ensure that they meet the needs of KUMC in the 21st century. The proposed project is a critical element the new vivarium and in realizing the new campus master plan and will provide tenant fit-out of planned shell space on the University of Kansas Medical Center Campus. Cancer center, University, and Health System leadership have made this building their highest collective priority and ~$150 Million have been raised have been raised thus far to fund the joint facility through philanthropic efforts and three Congressionally directed spending allocations.