Care4AD: A Comprehensive Care Coordination and Management Platform for Alzheimer Disease and Related Dementias

摘要 对痴呆症患者的护理需要对护理的提供进行持续有效的管理和协调 照顾者和家庭成员之间。一个强大的、技术驱动的护理管理解决方案， 协调可以显着减轻患者的负担，提高生活质量， 阿尔茨海默病（AD）。已经进行了一些尝试，使用技术来支持护理协调，但 没有综合系统来支持自我护理，帮助护理人员进行护理协调， 病人医疗团队内的信息共享。为了满足这一需求，BioSensics与 贝勒医学院（BCM）提议开发一个名为Care 4AD ™的综合护理平台。的 Care4AD平台将允许护理人员安排护理任务，监测身体活动和 日常生活（ADL），并促进及时完成ADL（例如，服药，定时服药，补水 和膳食，并出席预定的约会）通过视觉和语音提醒。 Care4AD将由四项技术组成，这些技术协同工作，以实现有效的护理协调。的 护理人员将使用Care4AD应用程序来协调护理，查看身体活动和ADL信息， 日程提醒Care4AD平板电脑作为患者家中的信息亭，用于显示计划的活动 和提醒，它还支持音频提醒和语音识别。Care4AD标签是一系列 无线传感器，其将被附接到家庭内的各种感兴趣的对象，以便于监测 日常生活的工具性活动。最后，Care4AD传感器是可穿戴传感器（基于现有的 可商购获得的技术），其监测身体活动和ADL，从 标签，并将数据传输到Care4AD平板电脑，该平板电脑作为收集的所有数据的数据网关 从传感器和标签。 BioSensics拥有成功完成该项目所需的经验， 将一个基于传感器的老年人远程监控平台PAMSys ™商业化。对于这个项目， 我们已经进行了三项初步研究，使用PAMSys监测个人的身体活动， 认知障碍此外，BioSensics已经开发出Care4AD标签的原型， 在这个项目中进一步完善。在第一阶段，我们将开发Care4AD平台的原型， 利益相关者访谈，以评估Care4AD的可行性和可接受性，并收集反馈， 用于改善平台。在第二阶段，我们将完成Care4AD的开发， 并进行随机对照临床研究，以评估是否使用Care4AD平台 减轻了工作的负担和压力，增加了对计划的ADL的依从性，并改善了身体状况。 患者的功能和生活质量。

ABSTRACT Care for persons with dementia requires constant and effective management and coordination of delivery of care between caregivers and family members. A robust, technology-driven solution for care management and coordination could significantly reduce the burden of caregiving and improve quality of life for patients with Alzheimer’s disease (AD). A few attempts have been made to use technology to support care coordination, but there is no integrated system to support self-care, assist caregivers with care coordination, and facilitate information sharing within a patient's caregiving team. In response to this need, BioSensics, in collaboration with Baylor College of Medicine (BCM), proposes to develop a comprehensive care platform called Care4AD™. The Care4AD platform will allow caregivers to schedule caregiving tasks, monitor physical activity and activities of daily living (ADL), and facilitate timely completion of ADLs (e.g., taking medication, scheduled toileting, hydration and meals, and attendance at scheduled appointments) through visual and voice reminders. Care4AD will consist of four technologies that work in tandem to enable effective care coordination. The Care4AD app will be used by caregivers to coordinate care, view physical activity and ADL information, and schedule reminders. The Care4AD tablet serves as a kiosk in the patient’s home to show scheduled activities and reminders, and it also supports audio reminders and voice recognition. Care4AD tags are a series of wireless sensors that will be attached to various objects of interest within the home to facilitate the monitoring of instrumental activities of daily living. Finally, the Care4AD sensor is a wearable sensor (based on existing commercially available technology from BioSensics) that monitors physical activity and ADLs, collects data from the tags, and transfers data to the Care4AD tablet, which serves as a data gateway for all the data collected from the sensor and tags. BioSensics has the requisite experience to successfully complete this project having developed and commercialized a sensor-based remote monitoring platform for older adults called PAMSys™. For this project, we have conducted three preliminary studies using PAMSys to monitor physical activity in individuals with cognitive impairment. In addition, BioSensics has already developed a prototype of the Care4AD tag, which will be further refined in this project. In Phase I, we will develop a prototype of the Care4AD platform and carry out stakeholder interviews to assess the feasibility and acceptability of Care4AD and gather feedback that will be used to improve the platform. In Phase II, we will complete the development of Care4AD, incorporating feedback from Phase I, and carry out a randomized controlled clinical study to evaluate if using the Care4AD platform reduces the burden and stress of caregiving, increases adherence to scheduled ADLs, and improves physical function and quality of life of patients.