HIV Prevention in the Family Drug Court

描述(由申请者提供)：这项以患者为导向的研究职业发展奖(K23)将使候选人，一名临床心理学家，成为青少年危险行为领域的独立研究人员，重点关注家庭过程、情绪调节、青少年药物滥用和艾滋病毒风险。这一培训奖项的首要目标是让候选人将研究成果应用于制定有效的艾滋病毒预防和对滥用药物的青少年罪犯的药物滥用干预措施。青少年罪犯滥用药物和艾滋病毒危险行为的风险比他们的非犯罪同龄人更高，其次是精神病理和情绪困扰的比率更高。更高的药物使用率和精神病理学大大增加了罪犯感染艾滋病毒的风险。尽管以家庭为基础的治疗在改变物质使用方面证明了一些效果，但它们未能针对青春期性危险行为，也没有关注可能对整个家庭的长期行为改变至关重要的结构(情绪调节)。因此，获奖期的研究目标是将目前针对滥用药物青少年罪犯的仅针对青少年的艾滋病毒预防干预调整(和测试)为针对滥用药物青少年罪犯的有效的基于家庭的情感管理艾滋病毒预防干预措施。这项研究将分为三个阶段。在第一阶段，将通过焦点小组和适应性干预的试点运行从45个青少年-父母二人组收集定性数据。在第二阶段，60名二元组将被随机分配到基于家庭的影响艾滋病毒预防或一般健康促进条件下，并进行基线和3个月的随访评估。为了估计以家庭为基础的干预措施的效果大小，将检查受试者在每种情况下干预反应的差异(例如，青少年药物使用和性风险的变化)。第三阶段将涉及项目总结和数据分析。候选人将通过五年的严格培训和强大的指导，在1)开发临床试验，2)治疗青少年药物滥用，3)开发以家庭为基础的干预措施，以解决家庭情绪失调，以及4)在青少年司法系统内工作，从而实现上述所有目标。这一项目的结果将为艾滋病毒感染风险极大的青少年人口今后的治疗开发工作提供信息。

DESCRIPTION (provided by applicant): This Mentored Patient-Oriented Research Career Development Award (K23) will enable the candidate, a clinical psychologist, to become an independent researcher in the area of adolescent risk behaviors, with a focus on family processes, emotion regulation, adolescent substance abuse and HIV risk. The overarching goal of this training award is for the candidate to apply research findings to the development of efficacious HIV prevention and substance abuse interventions for substance abusing juvenile offenders. Juvenile offenders are at elevated risk for substance abuse and HIV risk behaviors secondary to higher rates of psychopathology and emotional distress than their non-offending peers. Higher rates of substance use and psychopathology substantially increase offenders' risk for HIV infection. Although, family-based treatments have demonstrated some efficacy in changing substance use, they have failed to target adolescent sexual risk behavior and have not focused on a construct (emotion regulation) that may be central to long-term behavior change for the entire family. Thus, the research goal for the Award period is to adapt (and test) a current adolescent-only Affect Management HIV Prevention Intervention for Substance-Abusing Juvenile Offenders into an effective Family-Based Affect Management for HIV Prevention Intervention for Substance- Abusing Juvenile Offenders. This study will have three phases. In Phase 1, qualitative data will be collected from 45 adolescent-parent dyads via focus groups and pilot run-throughs of the adapted intervention. In Phase 2, 60 dyads will be randomized to either the Family-Based Affect HIV prevention or General Health Promotion condition with baseline and 3 month follow-up assessments. Differences in intervention response (e.g., changes in adolescent substance use and sexual risk) between subjects in each condition will be examined in order to estimate the effect size of the Family-Based intervention. Phase 3 will involve project summation and data analysis. The candidate will achieve all of the above with five years of rigorous training and strong mentorship in 1) developing clinical trials, 2) treating adolescent substance abuse, 3) developing family-based interventions that address family emotion dysregulation, and 4) working within the juvenile justice system. Future treatment development work for an adolescent population at great risk for HIV infection will be informed by the results of this project.