NATIONAL HIV BEHAVIORAL SURVEILLANCE SYSTEM

描述(由申请人提供)：马里兰州卫生与精神卫生局(DHMD)，艾滋病管理局要求美国卫生与公众服务部，疾病控制和预防中心(CDC)在三年内拨款1,417,943美元，以在马里兰州巴尔的摩实施国家艾滋病毒行为监测系统(NHBS)。NHBS是一项匿名研究，重点招募三个艾滋病毒感染风险人群：男男性行为者(MSM)、注射吸毒者(IDU)和艾滋病毒感染风险增加的异性恋者(HET)。这项研究将包括使用相同访谈工具的一系列三个横断面调查，将招募上述风险人群中的每一个。MSM招募工作将于2008年12月完成，IDU招募工作将于2009年12月完成，HET招募工作将于2010年12月完成。每个目标人群的拟议样本量至少为500名参与者。这项拟议的研究将包括一份详细的问卷，以收集有关人口统计、性和药物使用行为、艾滋病毒检测以及当地艾滋病毒预防计划服务利用情况的信息。调查问卷将在全国范围内标准化，并增加一些针对巴尔的摩的有限问题。这项研究还将提供艾滋病毒检测，利用FDA批准的艾滋病毒诊断测试和最近艾滋病毒血清转换的血清学测试算法(STARHS)来识别最近的感染。抽样和招募方法将根据每个目标人群(MSM、IDU和HET)进行适当选择，并将与疾病预防控制中心合作制定。男男性接触者招募将以场馆为基础。巴尔的摩市的公共场所(如酒吧、俱乐部等)将被随机抽样，符合条件的男性将被要求同意抽血和问卷调查。IDU招聘将使用受访者驱动抽样(RDS)。最初的注射吸毒者将通过关键的社区告密者招募，并在同意抽血后招募，然后将培训问卷以招募更多的注射吸毒者。接二连三的注射吸毒者招募将招募更多的注射吸毒者。接二连三的注射吸毒者招募将招募更多的注射吸毒者。HET的招募将通过场所招聘，如男男性接触者，或通过受访者驱动的抽样，如注射吸毒者，并将与疾病预防控制中心合作进行挑选。NHBS在巴尔的摩大都市区的活动将为衡量艾滋病毒危险行为以及规划和确定马里兰州艾滋病毒预防活动的目标提供宝贵的信息。美国疾病控制与预防中心提议在全国25个艾滋病毒高发区开展全国健康教育，合并后的数据将产生全国受影响最严重地区高危人群艾滋病毒风险行为的估计。

DESCRIPTION (provided by applicant): The Maryland Department to of Health and Mental Hygiene (DHMD), AIDS Administration is requesting $1,417,943 over three years from the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (CDC) to implement the National HIV Behavioral Surveillance System (NHBS) in the Baltimore, Maryland metropolitan area. The NHBS is an anonymous research study which focuses on recruiting three populations at risk for HIV infection: Men who have sex with men (MSM), injection drug users (IDU), and heterosexuals at increased risk for HIV infection (HET). This study will consist of a series of three cross-sectional surveys using the same interview instrument, which will recruit each of the above risk populations. MSM recruitment will be completed by December 2008, IDU recruitment by December 2009, and HET recruitment by December 2010. The proposed sample size for each of the target population is a minimum of 500 participants. The proposed study will include a detailed questionnaire to gather information on demographics, sexual and drug use behaviors, HIV testing, and utilization of local HIV prevention program services. The questionnaire will be standardized nationally, with the addition of a limited number of questions specific to Baltimore. The study will also offer HIV testing, utilizing both FDA approved HIV diagnostic tests and the Serologic Testing Algorithm for Recent HIV Seroconversion (STARHS) for the identification of recent infections. The sampling and recruitment methodologies will be selected as appropriate for each of the target populations (MSM, IDU, and HET) and will be developed in collaboration with the CDC. MSM recruitment will be venue-based. Public venues (e.g., bars, clubs, etc) in Baltimore City will be randomly sampled and eligible men will be requested to consent to a blood draw and a questionnaire. IDU recruitment will utilize respondent driven sampling (RDS). Initial IDU participants will be recruited through key community informants and after consenting to a blood draw and a questionnaire will then be trained to recruit additional IDUs. Successive waves of IDU recruits will recruit additional IDUs. Successive waves of IDU recruits will recruit additional IDUs. HET recruitment will be either through venue-based recruitment, as with MSM, or respondent driven sampling, as with IDUs, and will be selected in collaboration with the CDC. The NHBS activities in the Baltimore metropolitan area will produce valuable information for measuring HIV risk behaviors and for planning and targeting HIV prevention activities in Maryland. The CDC has proposed performing NHBS in 25 high HIV prevalence metropolitan areas nationwide, and the combined data will produce national estimates of HIV risk behaviors in high-risk populations in the most affected regions of the country.