1/2 The North Carolina Central University (NCCU)-Duke Cancer Institute (DCI) Cancer Disparities Translational Research Partnership (NCCU-DCICDTRP)
1/2 The North Carolina Central University (NCCU)-Duke Cancer Institute (DCI) Cancer Disparities Translational Research Partnership (NCCU-DCICDTRP)
批准号:
9355127
负责人:
Kevin Peter Williams
金额:
$6.88万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
关键词:
AddressAdvisory CommitteesAfrican AmericanAntineoplastic AgentsApplications GrantsAppointmentAreaCancer PatientClinicalClinical TrialsCollaborationsCommunicationCommunitiesComprehensive Cancer CenterDetectionDevelopmentEducational workshopEnsureEnvironmentEvaluationFacultyFeasibility StudiesGoalsGrantHistorically Black Colleges and UniversitiesHumanInstitutesInstitutionLaboratoriesLeadershipLibrariesLogisticsMaintenanceMalignant NeoplasmsMalignant neoplasm of prostateMentorsMentorshipMolecularNCI-Designated Cancer CenterNorth CarolinaOffice of Administrative ManagementOutcomePathway interactionsPeriodicityPhasePilot ProjectsPopulationPostdoctoral FellowProcessProgram EvaluationRaceRecordsRecruitment ActivityResearchResearch ActivityResearch InfrastructureResearch PersonnelResearch Project GrantsResearch SupportResearch TrainingResource SharingRetreatmentScientistStructureStudentsSystemTrainingTraining ProgramsTraining and EducationTranslational ResearchTranslationsUnderrepresented StudentsUnderserved StudentsUniversitiesWorkanticancer researchbasecancer health disparitycancer preventioncancer therapycareer developmentclinical caredrug developmenteducation researchexpectationexperiencegraduate studenthealth disparityhealth equityinflammatory breast cancerinnovationleadership developmentmeetingsmemberminority communitiesminority healthminority studentnext generationnovelnovel markernovel therapeuticsprogramsresearch and developmentsuccesssymposiumtherapeutic developmenttranslational cancer researchtranslational medicinetranslational research programtumorunderserved minority
中文摘要
北卡罗来纳州中央大学(NCCU)-杜克癌症差异转化研究伙伴关系
(NCCU-DCI CDTRP)专注于开发转化研究和培训的基础设施,
非裔美国人特定癌症的致死率增加。该计划建立在长期的
两个位于杜伦的机构之间的关系。NCCU是一个服务不足的健康机构
人口和代表性不足的学生(IUPS),附属于17名成员的大学,
北卡罗来纳州系统,而杜克癌症研究所(DCI)是一个国家癌症研究所指定的综合癌症
中心该伙伴关系将围绕加速规划和确定优先事项,重点是发展
一个双向的,互利的癌症研究教育计划(CREP),解决职业生涯
为研究生、博士后研究员和早期研究人员提供培训。规划将侧重于
建立定期讲习班、研讨会、务虚会和其他交流方式,并确定优先事项
将重点发展前瞻性机制,选择转化研究和培训
举措实施阶段将启动共同开发的合作试点项目,
预先计划过程,其重点是前列腺癌中差异的分子翻译方面,
非裔美国人的炎症性乳腺癌。NCCU和杜克之间的近25个共享资源将
提供给调查人员。社区参与将相互共同来自NCCU,NCCU直接
服务于少数民族社区,DCI的健康公平和差异办公室与现有的补充
与整个地区和州服务不足的少数民族人口一起制定方案。这一合作伙伴关系将
由一个由高级调查员组成的综合行政核心领导,他们将担任初级调查员的导师。
教师,博士后研究员和研究生,并将包括一个外部评估计划,以跟踪
影响和成果。该伙伴关系将由一个内部咨询委员会(IAC)、一个外部咨询委员会(IAC)和一个外部咨询委员会(IAC)指导。
科学咨询委员会(EAC)和社区咨询委员会(CAB)。咨询委员会的目标是
为NCCU-DUKE CDTRP伙伴关系提供:1)科学和行政领导; 2)行政
管理和支持; 3)管理委员会和执行行政决定; 4)规划
5)获得所有DCI和NCCU共享资源; 6)支持职业发展,
研究人员的指导; 7)支持赠款提交。总之,AC将促进翻译
通过与这些实验室的合作,在NCCU和DCI进行癌症差异研究。结构化
指导任命、研讨会和年度指导委员会会议将使领导层能够指导,
发展和建议生产性研究活动。AC将协助招募NCCU和杜克学生,
转化癌差异研究。该核心定义了评估进展的期望和指标
并将提供支持,让NCCU和杜克教师开发自我支持的研究计划。
英文摘要
The North Carolina Central University (NCCU) – Duke Cancer Disparities Translational Research Partnership
(NCCU-DCI CDTRP) is focused on developing infrastructure for translational research and training pertaining
to the increased lethality of specific cancers in African Americans. The Program is built on a long-standing
relationship between two Durham-based Institutions. NCCU is an Institution Serving Underserved health
disparity Populations and underrepresented Students (ISUPS), affiliated with the 17-member University of
North Carolina system, and the Duke Cancer Institute (DCI) is an NCI-designated Comprehensive Cancer
Center. The Partnership will develop around accelerated planning and priority-setting, focused on development
of a bi-directional, mutually beneficial Cancer Research Education Program (CREP) that addresses career
development for graduate students, postdoctoral fellows and early stage investigators. Planning will focus on
establishing regular workshops, seminars, retreats and additional modes of communication and Priority Setting
will focus on developing forward-looking mechanisms for selection of translational research and training
initiatives. The Implementation stage will launch with co-developed, collaborative Pilot Projects selected during
the pre-planning process, which focus on molecular translational aspects of disparities in prostate cancer and
inflammatory breast cancer in African Americans. Nearly 25 Shared Resources between NCCU and Duke will
be available to investigators. Community engagement will mutually co-emanate from NCCU, which directly
serves a minority community, and DCI’s Office of Health Equity and Disparities with complementary existing
programming with the underserved minority populations across the region and state. The Partnership will be
led by an integrated Administrative Core (AC) of senior investigators who will serve as mentors to junior
faculty, postdoctoral fellows and graduate students and will include an external Evaluation Program for tracking
impact and outcomes. The Partnership will be guided by an Internal Advisory Committee (IAC), an External
Scientific Advisory Committee (EAC) and a Community Advisory Board (CAB). The objectives of the AC are to
provide for the NCCU-DUKE CDTRP Partnership: 1) Scientific and administrative leadership; 2) Administrative
management and support; 3) Management of committees and implement administrative decisions; 4) Planning
and Evaluation; 5) Access to all DCI and NCCU shared resources; 6) Support career development and
mentorship of investigators; 7) Support for grant submissions. In summary, the AC will promote translational
cancer disparities research at NCCU and DCI through partnerships with such laboratories. Structured
mentoring appointments, seminars and annual steering committee meetings will allow leadership to mentor,
develop and advise productive research activities. The AC will assist in recruiting NCCU and Duke students to
translational cancer disparities research. This Core has defined expectations and metrics to assess progress
and will provide support to allow NCCU and Duke faculty to develop self-supporting research programs.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Prenatal Alcohol Exposure and Fetal Alcohol Spectrum Disorder
-
批准号:10541715
-
项目类别:
-
资助金额:$2.74万
-
财政年份:2022
-
负责人:Kevin Peter Williams
-
依托单位:
Prenatal Alcohol Exposure and Fetal Alcohol Spectrum Disorder
-
批准号:10705759
-
项目类别:
-
资助金额:$2.74万
-
财政年份:2022
-
负责人:Kevin Peter Williams
-
依托单位:
Project 2: Prenatal Alcohol Exposure (PAE) and Fetal Alcohol Spectrum Disorder (FASD)
-
批准号:10540966
-
项目类别:
-
资助金额:$18.65万
-
财政年份:2022
-
负责人:Kevin Peter Williams
-
依托单位:
Project 2: Prenatal Alcohol Exposure (PAE) and Fetal Alcohol Spectrum Disorder (FASD)
-
批准号:10705860
-
项目类别:
-
资助金额:$18.75万
-
财政年份:2022
-
负责人:Kevin Peter Williams
-
依托单位:
Immune Microenvironments and Hepatocyte Growth Factor Signaling Interactions in Breast Cancer Disparities
-
批准号:10708080
-
项目类别:
-
资助金额:$24.85万
-
财政年份:2017
-
负责人:Kevin Peter Williams
-
依托单位:
Immune Microenvironments and Hepatocyte Growth Factor Signaling Interactions in Breast Cancer Disparities
-
批准号:10556581
-
项目类别:
-
资助金额:$25.52万
-
财政年份:2017
-
负责人:Kevin Peter Williams
-
依托单位:
Identification of potent and selective GLI1 inhibitors
-
批准号:8523361
-
项目类别:
-
资助金额:$28.99万
-
财政年份:2013
-
负责人:Kevin Peter Williams
-
依托单位:
Identification of Specific Antagonists that Bind Hedgehog and Block its Activity
-
批准号:8100944
-
项目类别:
-
资助金额:$36.29万
-
财政年份:2011
-
负责人:Kevin Peter Williams
-
依托单位:
The Hedgehog Pathway and Inflammatory Breast Cancer
-
批准号:7666030
-
项目类别:
-
资助金额:$9.71万
-
财政年份:2008
-
负责人:Kevin Peter Williams
-
依托单位:
The Hedgehog Pathway and Inflammatory Breast Cancer
-
批准号:7427272
-
项目类别:
-
资助金额:$9.71万
-
财政年份:2008
-
负责人:Kevin Peter Williams
-
依托单位:
The Hedgehog Pathway and Inflammatory Breast Cancer
-
批准号:7922003
-
项目类别:
-
资助金额:$9.71万
-
财政年份:2008
-
负责人:Kevin Peter Williams
-
依托单位:
Project 2: Identifying and modulating genetic modifiers of GLI1 activation in inflammatory breast cancer.
-
批准号:9355129
-
项目类别:
-
资助金额:$8.59万
-
财政年份:--
-
负责人:Kevin Peter Williams
-
依托单位:
1/2 The North Carolina Central University (NCCU)-Duke Cancer Institute (DCI) Cancer Disparities Translational Research Partnership (NCCU-DCICDTRP)
-
批准号:9763339
-
项目类别:
-
资助金额:$6.71万
-
财政年份:--
-
负责人:Kevin Peter Williams
-
依托单位:
Project 2: Identifying and modulating genetic modifiers of GLI1 activation in inflammatory breast cancer.
-
批准号:9763346
-
项目类别:
-
资助金额:$8.11万
-
财政年份:--
-
负责人:Kevin Peter Williams
-
依托单位:
1/2 The North Carolina Central University (NCCU)-Duke Cancer Institute (DCI) Cancer Disparities Translational Research Partnership (NCCU-DCICDTRP)
-
批准号:9246379
-
项目类别:
-
资助金额:$7.15万
-
财政年份:--
-
负责人:Kevin Peter Williams
-
依托单位:
海外基金