Stanford Breast Metastasis Center Administrative Core

摘要/项目摘要 斯坦福大学乳腺转移中心（SBMC）行政核心将坚持以下原则： 我们的成功有赖一个协调良好和重点突出的多学科团队执行首要的研究。我们 核心团队拥有与来自世界各地的科学研究人员合作开展大型项目的良好记录， 多个领域，包括癌症生物学、免疫学、功能基因组学、计算生物学、生物信息学 乳腺肿瘤内科病理外科通过我们的行政核心，我们将提供 通过执行三个目标，确定并应对短期和长期需求的监督。我们的首要目标 是建立和维持一个有效和反应迅速的组织结构， NCI转移网络内活动的沟通和协调。对于内部监督，我们将 召集一个执行委员会，包括患者倡导者，外部咨询委员会，内部咨询委员会 委员会和指导委员会将定期开会，审查目前的进展情况，提出建议， 并监测未来的进展。所有SBMC研究者和工作人员将参加每两周一次的SBMC 在会议上，我们将听取PI、项目负责人和核心负责人的一般公告， 里程碑，听取我们的一位调查人员的更新和深入介绍，然后进行讨论。我们 将维持最新的邮寄名单和一个网站， 会议，主办活动日历，并提供数据和模型储存库的链接。我们的第二个目标是 建立并维护沟通和后勤战略，以便在内部进行透明和反应迅速的互动 SBMC、NCI MetNet和更广泛的科学界。促进内部的数据和方法交流 我们将积极参与MetNet研究者年会， 通过组织和参与合作活动和工作，为MetNet的活动做出贡献 组我们的第三个目标是促进对中心中期里程碑的评估，并在需要时实施 在NCI MetNet项目经理批准下修改里程碑的流程。我们将继续关注双- 通过我们的SBMC Military仪表板每周举行SBMC团队会议，该仪表板将总结我们 三个项目和核心。我们还将在NCI MetNet年会上报告里程碑的进展情况。三是 将在年度NCI现场评审期间对我们中心的绩效进行现场评估。最后，在不太可能的情况下， 如果我们在实现里程碑方面遇到延迟，我们将采取解决策略， 我们的团队和指导委员会，以及根据需要，EAC，IAC，其他MetNet中心的同事和 NCI

Abstract/Project Summary The Stanford Breast Metastasis Center (SBMC) Administrative Core will operate by upholding the principle that our success relies on a well coordinated and focused multidisciplinary team executing premier research. Our core team has an established track record of working on large scale projects with scientific investigators from multiple fields, including cancer biology, immunology, functional genomics, computational biology, bioinformatics and statistics, breast medical oncology, pathology, surgery. Through our Administrative Core, we will provide oversight that identifies and responds to short-term and long-term needs by executing three aims. Our first aim is to establish and maintain an effective and responsive organizational structure that provides proper communication and coordination of activities within the NCI Metastasis Network. For internal oversight, we will convene an Executive Committee, including patient advocates, External Advisory Committee, Internal Advisory Committee, and Steering Committee that will meet regularly to review current progress, make recommendations and monitor future progress. All SBMC investigators and staff will be expected to attend bi-weekly SBMC meetings where we will have general announcements by PIs, Project Leads and Core Leads, review our milestones, hear updates and an in-depth presentation from one of our investigators followed by discussion. We will maintain updated mailing lists and a website to disseminate announcements, archive summary notes from meetings, host a calendar of activities and provide links to data and model repositories. Our second aim is to establish and maintain a communication and logistics strategy for transparent and responsive interactions within the SBMC the NCI MetNet and the broader scientific community. To foster exchange of data and methods within other centers comprising the MetNet, we will actively participate in annual MetNet investigator meetings and contribute to the activities of the MetNet by organizing and participating in collaborative activities and working groups. Our third aim is to facilitate the evaluation of Center interim milestones and, if needed, implement processes to revise milestones with NCI MetNet Program Manager approval. We will monitor progress at bi- weekly SBMC team meetings through our SBMC Milestones Dashboard, which will summarize progress in our three Projects and Cores. We will also report progress on milestones at NCI MetNet annual meeting. Thirdly, we will host an onsite evaluation of our Center’s performance during annual NCI Site Reviews. Finally, in the unlikely event that we experience a delay in meeting our milestones, we will engage a resolution strategy that will involve our team and Steering Committee, and, as needed, the EAC, IAC, colleagues in other MetNet Centers and the NCI.