Career Enhancement Program

摘要-职业提升计划(CEP) 梅奥诊所孢子在卵巢癌中的目的是刺激、组织和促进严谨 翻译研究将有意义地减轻卵巢癌的负担。这一过程的关键部分 是提高卵巢癌翻译研究人员基础的质量和深度。在6-10年间 在资金方面，5名个人获得了职业提升计划(CEP)奖，并获得了1-2 资助年限(一名获奖者提供两年资助；四名获奖者提供一年资助)、指导团队和完整 获取孢子资源。我们的获奖者非常成功，有39篇同行评审的手稿 由6-10年级获奖者出版，3个已成功获得后续资金。全部五年6-10年 获奖者依赖于生物统计和生物信息学核心(核心C)，四名获奖者还与 生物标本和患者登记处(核心B)，三个与动物模型核心(核心D)。终极的 职业提升计划(CEP)的目标仍然是确定和指导新的 以及发展卵巢癌研究人员，他们具有明显的独立潜力 翻译研究人员以及吸引希望重新关注卵巢癌的知名科学家。 CEP为一年的支持提供高达100,000美元的支持(50,000美元来自孢子基金和匹配的 来自梅奥诊所癌症中心的50,000美元)；根据进展和继续，第二年是可能的 平移轨迹。特别强调吸引任职人数偏低的高素质个人。 在医学方面，包括妇女、少数群体和残疾人。识别和选择CEP 获奖者是通过严格的审查过程完成的，随后是密集的指导，整合到 正在进行的孢子活动和对每个人的进展的密切监督。除了一位主要导师外， 获奖者在临床、基础或人口科学方面有补充导师，以确保 翻译研究事业的发展。这充分利用了 蛋黄酱环境。CEP董事向梅奥卵巢诊所执行委员会报告 癌症孢子。在下一个资助期，卵巢孢子CEP将继续保持：(1)A 严格的候选人遴选制度；(2)初级导师对学员的全面指导；(3)支持 通过一个科学指导小组(每个获奖者的个人实习生指导委员会)，该小组由 在每个获奖者感兴趣的领域拥有专业知识的调查人员；以及(4)完全融入孢子， 包括访问所有科学核心。梅奥诊所提供了得天独厚的发展环境 从事卵巢癌的翻译研究。CEP使我们能够识别、指导和支持年轻人 未来将成为卵巢癌研究领导者的研究人员。

ABSTRACT – CAREER ENHANCEMENT PROGRAM (CEP) The purpose of the Mayo Clinic SPORE in Ovarian Cancer is to stimulate, organize and facilitate rigorous translational research that will meaningfully reduce the burden of ovarian cancer. A critical part of this process is to increase the quality and depth of the translational investigator base in ovarian cancer. During Years 6-10 of funding, five individuals received Career Enhancement Program (CEP) awards and were supported with 1-2 years of funding (one awardee with 2 years of funding; four with 1 year of funding), mentoring teams, and full access to SPORE resources. Our awardees have been highly successful, with 39 peer-reviewed manuscripts published by Year 6-10 awardees and 3 have successfully secured subsequent funding. All five Year 6-10 awardees relied upon the Biostatisics and Bioinformatics Core (Core C), four awardees also partnered with the Biospecimens and Patient Registry (Core B), and three with the Animal Models Core (Core D). The ultimate objectives of the Career Enhancement Program (CEP) continue to be the identification and mentoring of new and developing investigators in ovarian cancer who demonstrate clear potential to become independent translational researchers as well as attracting established scientists who wish to refocus on ovarian cancer. The CEP provides up to $100,000 for one year of support ($50,000 from SPORE funds and a matching $50,000 from Mayo Clinic Cancer Center); a second year is possible based on progress and continued translational trajectory. Special emphasis is placed on attracting highly qualified individuals underrepresented in medicine, including women, minorities, and persons with disabilities. Identifying and selecting CEP awardees is accomplished through a rigorous review process, followed by intense mentoring, integration into ongoing SPORE activities and close oversight of each individual’s progress. In addition to a primary mentor, awardees have complementary mentors in clinical, basic or population sciences necessary to ensure development of a translational research career. This capitalizes on numerous strengths present within the Mayo environment. The CEP directorship reports to the Executive Committee of the Mayo Clinic Ovarian Cancer SPORE. During the next funding period, the Ovarian SPORE CEP will continue to maintain: (1) A stringent candidate selection system; (2) comprehensive trainee guidance by a primary mentor; (3) support through a scientific mentoring group (each awardee’s Individual Trainee Mentorship Committee) comprised of investigators with expertise in each awardee‘s area of interest; and (4) full integration into the SPORE, including access to all scientific Cores. Mayo Clinic provides an exceptional environment for developing careers in translational research in ovarian cancer. The CEP allows us to identify, mentor, and support young investigators who will become future leaders in ovarian cancer research.