Primary Immune Deficiency Treatment Consortium Administrative Unit

PIDTC将有几个级别， 负责决策和管理（图1）。行政股 在Morton J.科万的指导下，PI负责PIDTC的整体管理。博士 科万的背景和经验详见第V节总体临床研究 计划、领导力和资源。行政单位将管理中心 合同，通过招募和参与科学研究， 计划委员会，与中心数据经理沟通，在以下方面支持中心 获得IRB批准并向USIDNET、CIBMTR和DMCC提交数据，以及 安排电话会议和前往RDCRC会议。作为PI，科万博士将负责 对联合体进行全面管理。他将领导PIDTC的行政股， 领导指导委员会和科学规划委员会。他将裁决 并将确保咨询委员会和ORD/NIAID管理人员 及时了解PIDTC的进展情况，他将与NIAID和ORD管理员合作， 其他联营体董事，以确保实现联营体的目标。他还将代表 PIDTC在ASBMT，BMTCTN和PBMTC以及美国和加拿大以外的其他团体， 特别是EBMT和ESID的免疫缺陷委员会，以及沿着Pis项目 co-Pi代表PIDTC与RDCRC管理员和其他PI。

The PIDTC will have several levels of responsibility for decision-making and administration (Figure 1). The Administrative Unit under the direction of Morton J. Cowan, PI, is responsible for the overall administration of the PIDTC. Dr. Cowan's background and experience is provided in detail in Section V. Overall Clinical Research Program, Leadership and Resources of the proposal. The Administrative Unit will manage center contracts, monitor individual center activities through enrollment and participation on the Scientific Planning Committee, communication with center data managers, support of centers with respect to obtaining IRB approval and submission of data to the USIDNET, CIBMTR and DMCC, and arrangement of conference calls and travel to RDCRC meetings. As PI, Dr. Cowan will be responsible for the overall management of the consortium. He will direct the Administrative Unit of the PIDTC and lead the Steering Committee and the Scientific Planning Committee. He will adjudicate conflicts within the consortium and will ensure that the Advisory Committee and ORD/NIAID administrators are kept up to date with the progress of the PIDTC and he will work with NIAID and ORD administrators and other consortia directors to ensure that the goals of the consortia are met. He will also represent the PIDTC in the ASBMT, BMTCTN and PBMTC and with other groups outside the US and Canada, in particular, the Immunodeficiency Committee of the EBMT and the ESID and along with Project Pis and the co-Pi represent the PIDTC with the RDCRC administrators and other Pis.