New antimalarial drug leads targeting multiple species and life cycle stages

疟疾每年造成约2亿临床病例和43万人死亡。预防和治疗依赖于药物，然而疟疾寄生虫的耐药性是一个巨大的问题。为了解决这个问题，并致力于消除疟疾，我们需要开发新的药物。该项目通过调查CSIRO开发的新化合物在其复杂生命周期的不同阶段杀死感染人类的疟疾寄生虫的能力，解决了这一重要的健康需求。

Malaria causes ~200 million clinical cases and >430,000 deaths annually. Prevention and treatment relies on drugs, however malaria parasite drug resistance is an enormous problem. To address this issue, and aim towards eliminating malaria, we need to develop new drugs. This project addresses this important health need by investigating the ability of new chemical compounds, developed at CSIRO, to kill human-infecting malaria parasites during different parts of their complicated lifecycles.