Application of new chemistry approaches for antimalarial drug discovery

每年约有100万人死于疟疾。目前还没有疫苗，由于这种高度适应性的寄生虫的抗药性，许多可用的药物正在变得不那么有效。我的目标是开发新的化学药物类别，以抑制疟疾寄生虫中与现有药物不同的靶点。除此之外，我的目标是改进目前使用新的化学方法和活体寄生虫分析评估抗疟疾药物效果的系统。

Malaria kills approximately one million people annually. Currently there no vaccine and many of the available drugs are becoming less effective due the resistance of this highly adaptable parasite. My aim is to develop new chemical classes of drugs that inhibit different targets in the malaria parasite to the currently available drugs. In addition to this I aim to improve the present systems for assessing antimalarial drug effects using new chemical approaches and live parasite assays.