Animal Models Core

动物模型模块 摘要 动物模型单元的目标是增强个人调查人员的能力 在视觉科学方面进行前沿研究，包括动物的产生和特征 疾病的模型。我们的目标是：1)提供进行动物实验所需的资源、支持和培训 研究水平超过任何单个实验室的能力；2)促进整个国家的联合领导 通过共享资源、技术和专业知识使视觉科学家社区；以及3)参与 同事进行视力研究，包括支持下一代基础和临床医生 科学家。为了实现这些目标，本单元将支持配备最先进的- ART器械，包括手术设备和形态和功能器械 对动物眼睛的分析。该单元将由经验丰富的人员监督和操作， 在进行广泛的动物研究方面的专业知识和对相关监管的深入了解 条件。这些共享资源将为有经验的用户和新手用户打开新的研究可能性， 并将成为促进我们广泛研究社区之间互动的平台。

Animal Models Module Abstract The objective of the Animal Models Module is to enhance the capabilities of individual investigators to conduct cutting edge research in the vision sciences, which involves generation and characterization of animal models of disease. Our Aims are: 1) to provide resources, support and training required for conducting animal studies at the level exceeding the capabilities of any individual laboratory; 2) to promote collegiality across the community of vision scientists through sharing resources, techniques and expertise; and 3) to engage colleagues into conducting vision research, including support of the next generation of basic and clinician scientists. To achieve these Aims, this Module will support sophisticated facilities equipped with state-of-the- art instrumentation, including surgical equipment and instrumentation for morphological and functional analyses of animal eyes. The Module will be supervised and operated by highly experienced personnel, with expertise in conducting a broad array of animal studies and deep understanding of associated regulatory conditions. These shared resources will open new research possibilities for both experienced and novice users, and will serve as a platform for fostering interactions among a broad swath of our research community.