Project 1

摘要：项目1（P1） 背景：社交媒体是接触新型电子烟产品的无处不在的渠道，特别是对于 青年然而，几乎没有证据表明社交媒体上描绘的电子烟产品多样性， 社交媒体对烟草产品使用的影响。P1旨在为FDA提供以下目标 监管使用社交媒体作为平台，了解电子烟产品的多样性，并告知监管 通过保护脆弱的年轻非用户，同时考虑影响， 对已经转向（或有兴趣转向）电子烟的成年吸烟者。方法：两个复合物- 初步研究将针对两个目标。目标1。用电子烟分析连续收集的社交媒体帖子 和其他烟草产品相关的关键词，以确定指示产品趋势的出现模式 市场营销，关于电子烟产品的对话，以及它们多样化的产品特性。为此，瞄准 1将审查与针对非烟草使用者的面向青年的帖子同时出现的新关键词和主题， 以及针对当前吸烟者的关于转向电子烟的健康导向帖子。P1检验假设 将有关于电子烟产品的帖子以面向青年的主题（即，关于电子烟的味道， vape云，折扣和卡通），往往会共同发生，这样的主题将是 不太可能与具有健康导向主题的电子烟产品上的帖子同时出现（例如，关于减少索赔 电子烟对自己和他人的危害，或关于戒烟）。P1还检验了信息 以年轻人为导向的主题将产生更多的用户参与（喜欢）和传播（转发，分享） 比没有它们的信息更重要目标2.为了确定是否参与（例如，发布，喜欢，分享）在e- 与青少年相关的社交媒体，特别是包含上述面向青年的主题的帖子， 与青少年和年轻人的烟草产品易感性和使用有关。P1将分析公开可用的 TCORS中心范围队列（招募）参与者生成的电子烟相关社交媒体帖子 在人口核心的支持下），并将数据与关于烟草制品使用的调查答复联系起来。P1测试 假设参与者参与并传播面向青年的电子烟草信息， 香烟随后将更有可能报告向更高水平的烟草产品使用过渡。整合 主题为“产品与人群的交叉点”：P1将研究产品多样性领域 在其他USC-TCORS项目中研究。P1也可能在Aim 1中识别出产品多样性的新领域。 P1将从社会媒体信息的主题角度解决人口多样性问题， 主题旨在吸引有兴趣转向低风险产品的人群与弱势青年 不使用烟草制品的人。FDA科学领域：行为和营销。

ABSTRACT: PROJECT 1 (P1) Background: Social media is a ubiquitous channel of exposure to novel e-cigarette products, particularly for youth. Yet, there is little evidence characterizing e-cigarette product diversity portrayed on social media and the impact of social media exposure to products on tobacco product use. P1 aims to provide FDA with targets for regulation using social media as a platform to understand e-cigarette product diversity, and to inform regulation that benefits the ‘population as a whole’ by protecting vulnerable young non-users while also considering impact on adult smokers who have switched (or are interested in switching) to e-cigarettes. Method: Two complemen- tary studies will address two aims. Aim 1. To analyze continuously collected social media posts with e-cigarette and other tobacco product-related keywords to determine patterns of occurrences that indicate trends in product marketing, conversations about e-cigarette products, and their diverse product characteristics. To this end, Aim 1 will examine new keywords and themes that co-occur with youth-oriented posts aimed at non-tobacco-users, and health-oriented posts aimed at current smokers regarding switching to e-cigarettes. P1 tests the hypothesis that there will be postings on e-cigarette products with youth-oriented themes (i.e., about e-cigarette flavors, vape clouds, discounts, and cartoons) that tend to co-occur with one another, and that such themes will be unlikely to co-occur with postings on e-cigarette products with health-oriented themes (e.g., claims about reduced harm of e-cigarettes to self and others, or about smoking cessation). P1 also tests the hypothesis that messages with youth-oriented themes will produce more user engagement (likes) and dissemination (retweets, shares) than messages without them. Aim 2. To determine whether participation (e.g., posting, liking, sharing) in e- cigarette-related social media, especially posts that contain youth-oriented themes described above, is associ- ated with tobacco product susceptibility and use among youth and young adults. P1 will analyze publicly available e-cigarette-related social media postings generated by participants in the TCORS’ Center-Wide cohort (recruited with support from the Population Core) and link the data to survey responses on tobacco product use. P1 tests the hypothesis that participants who engage with and disseminate youth-oriented tobacco messages about e- cigarettes will subsequently be more likely to report transitions to higher levels of tobacco product use. Integra- tion with “Intersections of Products with Populations” theme: P1 will study domains of product diversity studied in other USC-TCORS projects. P1 also is likely to identify novel domains of product diversity in Aim 1. P1 will address population diversity from a thematic perspective in social media messages by contrasting post- ings with themes meant to engage populations interested in switching to a lower risk product vs. vulnerable youth who are not using tobacco products. FDA Scientific domains addressed: Behavior and Marketing.