Population Core

核心人口

• 批准号: 10252837
• 负责人: Jennifer Beth Unger
• 金额: $ 90.16万
• 依托单位: UNIVERSITY OF SOUTHERN CALIFORNIA
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-19 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10252837
• 关键词: Address; Adolescence; Adolescent; Age; Archives; Award; Behavior; California; Characteristics; Child Health; Cohort Analysis; Collaborations; Complement; Confidential Information; Data; Data Analyses; Data Collection; Database Management Systems; Databases; Development; Electronic cigarette; Enrollment; Ensure; Epidemiology; Exposure to; Funding; Goals; Happiness; Health; Health Surveys; Human; Infrastructure; Laboratory Study; Learning; Length; Marketing; Measurement; Meta-Analysis; Methods; Participant; Pattern; Pennsylvania; Population; Population Assessment of Tobacco and Health; Population Database; Population Heterogeneity; Positioning Attribute; Preventive Medicine; Recreation; Regulation; Research; Research Personnel; Resources; Sampling; San Francisco; Schools; Science; Scientist; Smoker; Smoking; Subgroup; Sum; Surveys; Target Populations; Testing; Texas; Tobacco; Tobacco use; Universities; Update; Virginia; Vulnerable Populations; Work; Youth; aged; behavior observation; career; cohort; community based participatory research; data integration; design; early adolescence; electronic cigarette use; experience; follow-up; member; ninth grade; non-smoking; recruit; response; smoking cessation; social media; tobacco products; tobacco regulatory science; trend; young adult

Abstract: Population Core The projects in the USC-TCORS will require access to population resources with sufficient representation of tobacco product exposures, population subgroups, and longitudinal follow-up. The USC-TCORS Population Core (PC) will provide the Center with a sufficiently large, diverse, and well-followed sample to address the proposed scientific goals. We leverage data from a highly successful 2013-2018 initial funding period, in which we developed and tracked two cohorts with excellent retention. For 2018-2023, PC proposes the following aims. Aim 1. Expand, follow, track, and assess a Center-wide combined cohort. The PC will leverage data collected during the current award from two samples of adolescents, now young adults, for additional follow-up: (i) the Children's Health Study (CHS), which has extensive smoking information collected through schools since early adolescence, and complete information on tobacco product use starting at age 16-18 years; CHS participants will be aged 20-22 in 2018 (N=1,366); and (ii) the Happiness and Health (H&H) study, which has comprehensive tobacco product use information and covariates since enrollment in 2013 at age 14; H&H par- ticipants will be aged 18-19 in 2018 (N=2,534). Using now well-established methods, we will also recruit a new younger sample, the Trends in Tobacco Use Survey (TITUS) study, from 9th grade classrooms (age 14) in schools where CHS and H&H were originally drawn from (N=2,500). We will integrate these three resources into combined Center-wide cohort of 6,400 youth and young adults. The PC will conduct annual surveys on the Center-wide cohort to serve P1 and P3 aims, utilizing a common electronic survey infrastructure developed in partnership with the Administrative Core and ensuring common survey items across projects. The PC will also collect and manage a database of cohort data to be made available for the other projects, Rapid Re- sponse Projects, collaborations with other TCORSs, and junior investigator pilots (from the Career Enhance- ment Core). The database will be used for secondary data analysis projects and to identify populations with selected characteristics for recruitment into P4. The database will also be drawn upon for shared aims regard- ing social media exposure and tobacco use for P1 and P3. Finally, the database will be a resource for addi- tional original data collection projects. Aim 2. Facilitate access to other population resources outside of the Center-wide cohort within the USC Department of Preventive Medicine. The PC will enhance existing connec- tions with and access to population cohorts and archival databases including numerous diverse samples. In sum, PC cohorts will provide an unmatched population resource in terms of diversity, follow-up length, meas- urement intensity, and richness of data. Our resource will complement and provide unique information to other large samples such as the Population Assessment of Tobacco and Health survey by providing population di- versity, product diversity assessment, and tobacco product exposure analysis that is not otherwise available.

摘要：人口核心 南加州大学-TCORS的项目将需要获得人口资源， 烟草制品暴露、人群亚组和纵向随访。USC-TCORS人群 核心（PC）将为中心提供一个足够大的，多样化的，以及遵循的样本，以解决 提出科学目标。我们利用2013-2018年非常成功的初始融资期的数据，其中 我们开发并跟踪了两个保持率很高的队列。对于2018-2023年，PC提出以下建议 目标。目标1。扩展、随访、跟踪和评估中心范围内的合并队列。PC将利用数据 在本奖项期间从两个青少年样本中收集，现在是年轻的成年人，进行额外的随访： (i)儿童健康研究（CHS），该研究通过学校收集了广泛的吸烟信息 从青春期早期开始，以及从16-18岁开始使用烟草制品的完整信息; 参与者将在2018年年龄为20-22岁（N= 1，366）;（ii）幸福与健康（H&H）研究，该研究 自2013年14岁入组以来的全面烟草制品使用信息和协变量; H&H标准 2018年的参与者年龄为18-19岁（N= 2，534）。我们也将采用目前行之有效的方法， 年轻的样本，烟草使用趋势调查（TITUS）研究，从9年级教室（14岁）， CHS和H&H最初来自的学校（N= 2，500）。我们将整合这三种资源 将6,400名青少年和年轻成年人纳入中心范围内的联合队列。筹委会将每年进行调查， 利用开发的通用电子调查基础设施，为P1和P3目标服务 与行政核心合作，确保项目间的共同调查项目。PC将 还收集和管理队列数据的数据库，以提供给其他项目，快速重新， 赞助项目，与其他TCORS的合作，以及初级调查员飞行员（来自职业提升- 核心）。该数据库将用于二级数据分析项目，并用于确定 为征聘到P4工作人员选定的特征。该数据库也将被用于共同目标- P1和P3的社交媒体曝光和烟草使用。最后，数据库将是一个资源， 国家原始数据收集项目。目标2.促进获得人口领域以外的其他人口资源 南加州大学预防医学部的全中心队列。PC将加强现有的连接， 与人口队列和档案数据库建立联系，并可利用这些数据库，包括许多不同的样本。在 总而言之，PC队列将在多样性、随访时间、测量 测量强度和数据的丰富性。我们的资源将补充和提供独特的信息，以其他 大样本，如烟草与健康人口评估调查，提供人口数据， 多样性、产品多样性评估和烟草产品暴露分析，这些都是其他方法无法提供的。