Columbia University Graduate Training Program in Microbiology and Immunology

这份重新提交的申请要求美国国立卫生研究院为哥伦比亚大学博士前研究生提供新的支持 微生物学和免疫学培训计划。请求支助四个培训补助金职位，每个职位 按照上一个周期，这是一年。我们的博士授予计划为博士后实习生提供了独特的 在广泛而有凝聚力的科学探究计划中获得个性化培训的机会 免疫系统，宿主对感染的反应，病原体生物学，微生物学的系统方法和 免疫学、癌症免疫学、人类免疫学、移植以及微生物和 免疫细胞复制。超越了分隔微生物学和免疫学的传统界限， 我们的研究兴趣集中在三个跨学科主题上：i)免疫细胞和组织开发以及 动态平衡，包括对人类免疫学的主要强调；ii)病原体生物学和宿主反应；以及 三)DNA复制和修复及其与细胞增殖的联系，包括影响 免疫系统。我们的23名导师，主要在基础科学或医学系任职 哥伦比亚大学欧文医学中心(CUIMC)，展示了杰出的研究和培训记录。 大多数教授都被任命为微生物学和免疫学系的成员，该系负责管理这项工作 程序。学员学习微生物学和免疫学、分子遗传学、生物化学、细胞 生物学、计算和数量生物学，以及研究中负责任的行为。学生也可以注册 关于科学写作、拨款准备和评论的研讨会。学员还必须通过资格赛 测试他们为假设驱动的项目制定和辩护的能力的考试。我们的研究生课程 由我们的主任David Fidock博士和副主任Uttiya Basu博士领导。我们的方案框架 包括一个咨询委员会，该委员会定期评估学员和培训师的表现、课程和 培训补助金合格申请者；初级培训员指导计划；以及外部审查委员会 由三名计划总监组成，他们定期提供反馈，帮助优化计划的有效性。在……里面 自从我们的研究生项目首次获得NIAID资助以来的六年里，我们一直在招聘一名 优秀的学生群体，平均GPA为3.6，平均全日制入学时间为21个月 为我们的TGE参赛者提供研究经验，他们占我们参赛者的90%。未被充分代表的少数民族， 我们积极寻求招聘的人，占我们队伍的17%。我们的项目正在蓬勃发展，这一点从 过去和现在实习生的特殊出版记录。超过95%的毕业生留在了 科学或与科学相关的领域。我们还受益于我们的院长和办公室的强有力的机构支持 研究生事务部，以及CUIMC的许多科学、教育和职业发展资源。 我们的研究生课程充满活力、严谨和丰富，致力于培养未来的领导者和创新者。 在微生物学和免疫学研究方面。

This resubmitted application requests renewed NIH support for the predoctoral Columbia University Graduate Training Program in Microbiology and Immunology. Support is requested for four training grant positions each year, as per the previous cycle. Our PhD granting program provides predoctoral trainees with a unique opportunity to obtain individualized training within a broad yet cohesive program of scientific inquiry into the immune system, host response to infection, pathogen biology, systems approaches to microbiology and immunology, cancer immunology, human immunology, transplantation, and processes of microbial and immune cell replication. Extending beyond traditional boundaries that separate microbiology and immunology, our research interests converge on three cross-disciplinary themes: i) immune cell and tissue development and homeostasis, including a major emphasis on human immunology; ii) pathogen biology and host response; and iii) DNA replication and repair and their links to cell proliferation, including cancerous processes affecting the immune system. Our 23 preceptors, with primary appointments in basic science or medical departments at the Columbia University Irving Medical Center (CUIMC), demonstrate outstanding research and training records. Most preceptors are appointed to the Department of Microbiology and Immunology, which administers this program. Trainees take courses in microbiology and immunology, molecular genetics, biochemistry, cell biology, computational and quantitative biology, and responsible conduct in research. Students also enroll in workshops on scientific writing, grant preparation, and critiquing. Trainees must also pass a qualifying examination that tests their ability to formulate and defend a hypothesis-driven project. Our graduate program is led by our Director Dr. David Fidock and Associate Director Dr. Uttiya Basu. Our programmatic framework includes an Advisory Committee that regularly evaluates student and trainer performance, the curriculum, and Training Grant Eligible applicants; a mentoring plan for junior trainers; and an External Review Board comprised of three Program Directors who provide regular feedback to help optimize program effectiveness. In the six years since our Graduate Program was first awarded NIAID funding, we have consistently recruited an excellent cohort of students, with a mean GPA of 3.6 and an average of 21 months of full-time incoming research experience for our TGE entrants, who constituted 90% of our entrants. Underrepresented minorities, who we actively seek to recruit, comprised 17% of our cohort. Our program is flourishing, as evidenced by the exceptional publication record of past and current trainees. Over >95% of our graduates have remained in science or science-related fields. We also benefit from strong institutional support from our Dean and the Office of Graduate Affairs, as well as the many scientific, educational and career development resources at CUIMC. Our dynamic, rigorous and enriching graduate program is committed to training future leaders and innovators in microbiology and immunology research.