Core A: Administrative Core

摘要-行政核心 行政核心（Admin Core）的主要目标是作为一个中心站点， 研究者之间的沟通和互动，以支持合作，外部科学 社区，并确保中心的有效治理和监督。我们的无墙中心（Our Center Without Walls） 中心）将由5个不同的地点组成。该中心的研究项目具有高度的互动性。的 互动将在不同层面上进行，从科学层面（信息和数据的交流， 资源和专门人员的分配，初级调查员的共同指导）到行政（组织） 与国家FTD中心的会议和互动）。此外，目标，研究策略和使用 内部执行委员会和外部顾问需要定期重新评估资源， 在实现中心目标方面取得最大进展。我们提出了四个具体目标。在目标1中，核心 帮助主任监督中心的治理和管理，包括实施战略， 促进各组成部分之间的沟通，并最大限度地利用内部和外部 资源该核心还将协调每个项目研究人员之间的沟通， 项目和核心，中心与内部执行指导委员会和外部 科学咨询委员会，以及中心与五个地点的管理部门之间的联系，NINDS 项目工作人员和其他国家FTD中心。在目标2中，核心将促进 项目和核心，并监测他们的进展，以实现该中心的既定目标，包括与 开发和维护一个基于网络的项目管理系统、一个公共网站和一个内联网的数据核心 以获取安全数据，并组织现场会议和电话会议。核心将开发和维护一个 基于网络的界面，帮助主任和指导委员会成员最大限度地生成和使用 资源，包括中心内外的资源。核心将确保中心活动符合 通过提供有关NIH法规的信息，了解联邦和机构法规，并及时提供报告 并向临床监督和执行指导委员会提供合规性更新。在目标3中， 将协调外部互动，促进与更广泛的研究和宣传的关系 通过促进与Tau联盟（TC），Gladstone以及更广泛的 科学界。在目标4中，核心小组将确保及时编写进度报告， 传播研究结果和材料，包括提供稿件的预先通知， 向NINDS项目官员提供出版物，并与NINDS通讯办公室合作， 突出显示中心的成就。

ABSTRACT — ADMINISTRATIVE CORE The main objective of the Administrative Core (Admin Core) is to serve as a central site to facilitate communication and interaction between the investigators to support collaboration, to the external scientific communities, and to ensure efficient governance and oversight of the Center. Our Center without Walls (the Center) will consist of 5 different sites. The research programs in the Center are highly interactive. The interactions will occur at different levels ranging from the scientific (exchange of information and data, sharing of resources and specialized personnel, co-mentoring of junior investigators) to the administrative (organization of meetings and interactions with national FTD centers). In addition, the goals, research strategies, and use of resources will need to be periodically reevaluated by internal executive committees and external advisors to maximize progress in achieving the aims of the Center. We propose four specific aims. In Aim 1, the Core will help the director oversee Center governance and management, including implementation of strategies to facilitate communication among the various components and maximize the use of internal and external resources. The core will also coordinate communications among the researchers in each project, between projects and the cores, between the Center and the internal Executive Steering Committee and the external Scientific Advisory Committee, and between the Center and the administration of the five sites, NINDS program staff, and the other national centers on FTD. In Aim 2, the core will promote exchanges among the projects and cores and monitor their progress toward the stated goals of the Center, including working with Data core to develop and maintain a web-based project management system, a public website and an intranet for secured data, and organize on-site meetings and teleconferences. The core will develop and maintain a web-based interface to help the director and Steering Committee members maximize the generation and use of resources, both within and external to the Center. The core will ensure that Center activities comply with federal and institutional regulations by providing information on NIH regulations and will provide timely reports and updates on compliance to the Clinical Oversight and Executive Steering Committees. In Aim 3, the core will coordinate external interactions and foster relationships with the broader research and advocacy communities by facilitating interactions with the Tau Consortium (TC), with Gladstone, and the broader scientific community. In Aim 4, the Core will ensure timely preparation of progress reports and the dissemination of research findings and materials, including providing advance notice of manuscripts and publications to the NINDS program officer and work with the NINDS Office of Communications on press releases highlighting Center accomplishments.