P30-Core Grant for Vision Research Core C

生物统计学和生物信息学（生物分析）核心的使命是提供现代生物信息学 亚特兰大视觉研究社区（AVRC）。生物分析指令 核心是为AVRC提供NEI R01资助的主要研究者（PI），资源（专业知识，工具， 培训和服务），通常不会通过个人NEI R01补助金获得。此外，我们促进 愿景核心赠款的高生产力和协作成员之间的互动。我们的模块 促进数据存储、策展、检索和管理，并维护安全和备份的服务器， 基于数据存档来处理大量生物数据。我们召集了一群信息学家， 计算机程序员/管理员开发/实施新的工具和服务。这些人员执行 数据分析，并指导他人使用这些工具。生物分析核心是核心的核心 活动从基于数据服务器的数据存储开始，最终进行分析。我们同心协力 与其他模块一起，引导对添加到系统中的每个新设备所生成的数据进行分析。 Vision Core的研究成果生物分析核心的具体目标包括： 1.提供比NEI更好的资源和更方便地访问最先进的分析工具- R01 PI可以单独提供或支持。 2.与PI协商确定项目范围、时间表和所需服务。 3.开展工作，否则需要雇用生物信息学和生物统计学专家， 对于R01预算来说不切实际。 4.为PI和相关人员提供更多日常任务的适当培训。 5.预先测试和收集来自前沿技术的数据和软件，以避免重复 多个PI的错误。

The mission of the Biostatistics and Bioinformatics (Bioanalysis) Core is to provide modern bioinformatics and statistical methods to the Atlanta Vision Research Community (AVRC). The directive for the Bioanalysis Core is to provide NEI R01-funded principal investigators (PIs) in the AVRC, the resources (expertise, tools, training, and services) that are not usually obtained through individual NEI R01 grants. In addition, we facilitate interactions among highly productive and collaborative members of the vision core grant. Our module facilitates data storage, curation, retrieval, and management, and maintaining a secure and backed up, server- based data archive to handle large sets of biological data. We have assembled a group of informaticists and computer programmers/administrators to develop/implement new tools and services. These personnel perform data analyses, and instruct others on the use of these tools. The Bioanalysis Core forms the heart of the core activities beginning with data server-based data storage and eventually analysis. We coordinate our efforts with other modules to lead in the analysis of data generated by each new piece of equipment added to the Vision Core's research endeavor. Specific Aims of the Bioanalysis Core include: 1. Provides better resources and more convenient access to state of the art analysis tools than an NEI- R01 PI could provide or support alone. 2. Consults with PIs to determine scope of a project, timeframe, services needed. 3. Conducts work that would otherwise require hiring of bioinformatics and biostatistics experts that is impractical for an R01 budget. 4. Provides training to PIs and personnel as appropriate for more routine tasks. 5. Pre-tests and troubleshoots data and software from bleeding edge technologies to avoid repeated mistakes by multiple individual PIs.