Joint Effects and Community-Level Characteristics in Estimating Cerebrovascular Risk Among HIV Infected and Uninfected Veterans

本研究的总体目标是确定邻里水平的影响， 脑血管病的个体水平联合特征沿着 （CeVD）艾滋病毒阳性和阴性退伍军人的结果。建议的流行病学 在艾滋病毒和CeVD研究中未得到充分利用的战略包括多层次 纳入社区一级特征（种族和民族隔离）的分析 沿着个人水平特征（艾滋病毒治疗，情绪障碍， 酒精/药物滥用/依赖）估计CeVD的发生率。这将是第一次 沿着考虑邻里层面与个体层面共同影响的研究 HIV和CeVD研究的特点。

The overall objective of this study is to determine the efect of neighborhood-level characteristics along with individual-level joint characteristics on cerebrovascular disease (CeVD) outcomes among HIV positive and negative veterans. The proposed epidemiologic strategy, which has been underutilized in HIV and CeVD research, includes multi-level analyses that incorporate a neighborhood-level characteristic (race and ethnic segregation) along with the joint efects of individual-level characteristics (HIV treatment, mood disorders, alcohol/drug abuse/dependence) in estimating the incidence of CeVD. This will be the frst study to consider neighborhood-level along with the joint efects of individual-level characteristics in HIV and CeVD research.