New methods and guidelines for the design, analysis and reporting of cluster-crossover and stepped wedge randomised trials in clinical and public health research

集群交叉和阶梯式楔形设计最近作为临床和公共卫生研究环境中使用的研究设计而出现。然而，尽管使用了统计分析方法，但对目前实践中使用的统计分析方法进行的方法论评估很少。拟议的研究将评估当前方法的正确性，并将为临床/健康研究人员提供最先进的、可辩护的试验设计、分析和报告方法的工具包。

Cluster crossover and stepped wedge designs have emerged recently as study designs used in clinical and public health research settings. However, despite their use there has been very little methodological assessment of the statistical analysis methods used in current practice. The proposed research will assess the correctness of current methods and will produce a toolkit of state-of-the art, defensible trial design, analysis and reporting methods for the clinical/health researcher.