Biostatistics Training in Cancer Research

摘要 这份申请是为了延续一个始于2002年的项目，用于培养四名博士生 癌症生物统计学在生物医学研究中，对训练有素的统计科学家的需求是巨大的， 美国各地生物统计学系的毕业生数量都没有达到这个水平。的 培训计划的目的是增加新一代癌症研究的参与， 生物统计学家不仅接受过现代统计学的强大方法的教育，而且还接受过生物学的教育 和癌症流行病学，目前关于疾病病因学的知识体系，它的检测， 预防、自然史和治疗。该培训计划将为生物统计学家提供必要的 科学知识，以了解癌症研究的当前问题，并在统计和 与癌症有关的流行病学技术和研究方法。培训计划的目标 是给那些正在获得博士学位的学生。在生物统计学或流行病学（一）一个坚实的理解 癌症生物学，（ii）与癌症科学家沟通和合作的经验和能力，（iii） 了解癌症的最新发展需要创新的统计研究和（iv）独立的 研究技能。跨学科的计划，将使学员获得知识和经验 在癌症研究领域，并作为生物统计学家参加了一项积极的研究计划， 生物统计学导师和癌症科学家的指导。将促进癌症研究经验 由癌症中心生物统计学，分析和生物信息学共享资源。除了有 生物统计学课程，学员须修读癌症流行病学、生物学及 遗传学强有力的方案活动包括一个专门设计的生物统计学研讨会课程， 癌症问题，期刊俱乐部，一年两次的务虚会，参观癌症研究实验室，并邀请 访客.该培训计划是基于生物统计学系，这是由国家评级 研究理事会在2010年作为顶级生物统计部门在美国。培训计划将吸引 学生主要来自生物统计学系，但也来自流行病学系。的 培训计划得到了来自生物统计学和流行病学系的17名初级教师的支持 和密歇根大学综合癌症中心的13名支持教师。

Abstract This application is for continuation of a program that first began in 2002, for training four pre-doctoral students in cancer biostatistics. The need for well trained statistical scientists in biomedical research is massive and it is not being met by the number of graduates being produced by biostatistics departments across the US. The aim of the training program is to increase the participation in cancer research of the new generation of biostatisticians who are educated not only in the powerful methods of modern statistics, but also in the biology and epidemiology of cancer, the current body of knowledge about the etiology of the disease, its detection, prevention, natural history and treatment. This training program will provide biostatisticians with the requisite scientific knowledge to understand current issues in cancer research, and training in statistical and epidemiological techniques and research methodology related to cancer. The goals of the training program are to give students who are obtaining a Ph.D. in Biostatistics or Epidemiology (i) a solid understanding of cancer biology, (ii) experience and ability to communicate and collaborate with cancer scientists, (iii) understanding of recent developments in cancer requiring innovative statistical research and (iv) independent research skills. The interdisciplinary program that will enable the trainees to obtain knowledge and experience in an area of cancer research and to participate as a biostatistician in an active research program under the direction of a mentor in biostatistics and a cancer scientist. The cancer research experience will be facilitated by the Cancer Center Biostatistics, Analytics and Bioinformatics Shared Resource. In addition to the biostatistics courses, the trainees will be required to take courses in cancer epidemiology, biology and genetics. The strong programmatic activities include a specifically designed seminar course on biostatistical issues in cancer, a journal club, a bi-annual retreat, visits to cancer research labs and meetings with invited visitors. The training program is based in the Department of Biostatistics, which was rated by the National Research Council in 2010 as the top Biostatistics department in the US. The training program will draw students primarily from the department of Biostatistics, but also from the department of Epidemiology. The training program is supported by 17 Primary Faculty from the departments of Biostatistics and Epidemiology and 13 Supporting Faculty from the University of Michigan Comprehensive Cancer Center.