Increasing the Social Science Impact of Biomedical Research

培训核心（TL 1）-摘要 斯克里普斯翻译科学研究所（STSI）TL 1培训计划的目标是提供前， 博士后研究员在尖端的方法和分析方法的独特经验，旨在 使其在转化和精确医学的复杂竞技场中有效。该计划隶属于 一个基础研究机构，而不是一个医学院，使它具有独特的地位和优势， 基础研究，药物发现和开发，临床前模型和机械见解的教育， 疾病非常强调团队科学和来自斯克里普斯的主治医生的整合 在所有项目的健康，该计划将产生领导者进行变革所需的技能， 转化科学到目前为止，这个年轻的项目只培养了博士前研究员。所有8个人都有 毕业后，在此过程中发表了31篇论文，仍留在科学领域，6名学生仍得到支持 被节目。在此成功的基础上，并在对交付中存在的瓶颈进行彻底分析后， 有效的转化研究，我们将实施一系列的变化，以加强我们的计划， 三个具体目标： 具体目标1。扩展当前的课程，以提供尖端的临床转化研究 能力和加强指导。为实现这一目标，将增加新的课程， 解决最新的科学和医学问题。指导将通过协调每一个 围绕每月的进度报告会议制定项目。 具体目标2。扩大目前的TL 1计划，以提供学员的全面代表性 成功的临床转化项目所必需的。除了我们成功的博士预科课程， 我们将包括一个为期3年的博士后通道，以增加博士学位以外的翻译能力。 具体目标3。增加我们培训计划的多样性。精准医疗无法实现， 对多样性的敏锐感知我们的努力将针对增加任职人数不足的人数， 学生在我们的计划增加招聘关系与高校和研究生院服务于这些 人口。 该计划的这些变化和演变发生在一个非凡的时刻， TSRI：整合了加州生物医学研究所（Calibr）的药物发现和 发展研究所，将允许在该领域的TL 1学生的培训，并建立一个斯克里普斯 2018年生物科学研究学院。

Training Core (TL1) - Abstract The objective of the Scripps Translational Science Institute (STSI) TL1 training program is to give pre- and postdoctoral fellows a unique experience in cutting-edge methodological and analytical approaches aimed at making them efficient in the complex arena of translational and precision medicine. This program’s affiliation to a basic research institute instead of a medical school gives it a unique position and strength by offering education in basic research, drug discovery and development, preclinical models, and mechanistic insights into diseases. With a strong emphasis on team science and the integration of attending physicians from Scripps Health in all projects, this program will produce leaders with the skills required to conduct transformative translational science. To date, this young program has trained only predoctoral fellows. All 8 who have graduated, publishing 31 papers in the process, have remained in science, and 6 students remain supported by the program. Based on this success, and after thorough analysis of what bottlenecks remain in the delivery of efficient translational research, we will implement a series of changes to enhance our program by carrying out 3 specific aims: Specific Aim 1. Expand the current coursework to deliver cutting-edge clinical-translational research competencies and enhance mentorship. This objective will be achieved by adding new courses aimed at addressing the most current scientific and medical issues. Mentorship will be reinforced by coordinating each project around monthly meetings with presentation of progress. Specific Aim 2. Expand the current TL1 program to provide the full representation of trainees necessary for successful clinical-translational projects. In addition to our successful predoctoral program, we will include a 3-year postdoctoral pathway to add translational competencies beyond PhD completion. Specific Aim 3. Increase diversity in our training program. Precision medicine cannot be achieved without an acute perception of diversity. Our efforts will be targeted at increasing the number of underrepresented students in our program by adding recruitment relationships with colleges and graduate schools serving these populations. These changes and evolution of the program come at a remarkable time with two exciting developments at TSRI: the integration of the California Institute for Biomedical Research (Calibr) a drug-discovery and development institute that will allow training of TL1 students in that field, and the creation of a Scripps Research Biosciences College in 2018.