Priming the Pump: Training Physician-Scientists in Translational Psychiatry

摘要（家长奖） 该提案旨在继续和改进住院医师培训研究轨道， 明确的目标是招募MD/PhD和医学毕业生，并在开展 research.该计划提供早期接触精神病学的临床研究，以刺激 我们的基础科学培训生对转化研究的兴趣。此外，研究跟踪 居民有14.5个月的受保护时间进行独立的研究项目。这几个月 由PI监督的强化指导，作为“元导师”， 以及一个定制的课程，重点是道德，统计，研究设计和原则， 翻译研究所有这些都是在满足ACGME临床培训要求的同时实现的， 精神病学的毕业生是合格的这种做法旨在纠正目前的 MD/PhD经常在中断后面临“重新开始”研究的情况 这是由临床培训的需要而产生的。我们已经有初步证据表明我们的四年计划 允许研究轨道居民“跳跃开始”他们的研究生涯，使他们更好地 为研究奖学金和K奖过程做好准备，最终将其设置为 作为独立调查员的成功职业。作为额外的奖励，培训基础设施 由研究轨道计划建立提供了一个机会，多个“坡道”， 没有先前研究经验的居民探索研究和发展基本的研究技能。 通过这一计划，我们预计将加强医生科学家的管道准备， 进行精神病学的转化研究，这是NIMH的一个关键目标。

Abstract (of Parent Award) This proposal aims to continue and improve upon a residency training research track with the explicit goal of recruiting MD/PhD and medical graduates with a track record in conducting research. The program provides early exposure to clinical research in psychiatry to stimulate interest in translational research among our basic science trainees. In addition, research track residents have 14.5 months of protected time for an independent research project. These months are augmented by intensive mentoring, overseen by the PIs, functioning as “meta-mentors,” as well as a customized curriculum focused on ethics, statistics, research design, and principles of translational research. All this is attained while meeting ACGME clinical training requirements so that graduates are board-eligible in psychiatry. This approach is intended to remedy the current state of affairs wherein MD/PhDs often are faced with “re-starting” their research after a hiatus created by the need for clinical training. We already have early evidence that our 4-year program permits research track residents to “jump start” their research career, rendering them better prepared for research fellowships and the K-award process, ultimately setting them up for successful careers as independent investigators. As an added bonus, the training infrastructure established by the research track program provides an opportunity for multiple “on-ramps” for residents without prior research experience to explore research and develop basic research skills. Through this program we anticipate enhancing the pipeline of physician-scientists prepared to conduct translational research in psychiatry, a key goal of the NIMH.