The Duke Multidisciplinary Training Program in Pediatric Lung Disease

描述(由申请人提供)： 作为一个国家，我们正面临着越来越多的慢性呼吸道疾病的流行，这些疾病起源于童年。然而，具有研究呼吸系统疾病基本发病机制或开发或批判性评估新疗法的专业知识的儿科肺科医生严重短缺。在NHLBI资助的220多个T32研究培训项目中，只有3个NIH资助的T32项目致力于儿科肺内科医生-科学家的研究培训。杜克儿科肺部疾病多学科培训计划旨在将儿科肺部研究员培养成训练有素的内科科学家，他们将成为未来基础、翻译和临床研究的领导者。我们有两个赛道：基础研究赛道和临床研究赛道。我们的基础研究轨道得到了成功研究人员的支持，他们的研究重点是肺细胞和分子生物学、基因组学、肺损伤、炎症、免疫学和修复、肺发育和肺干细胞生物学，这些都影响了作为肺部疾病病理生理学基础的科学。研究员在实验室有密集的实践经验，并参加教学课程，以补充这一培训。我们的临床研究部分得到了杜克大学临床研究培训计划的大力支持，研究员有机会参加健康科学硕士课程以及生物统计学和流行病学的临床研究和研究生课程。丰富的多学科环境得到了所有参加每月三次研讨会系列的研究员的支持。该计划的领导由杜克大学医学中心学院组成的内部咨询委员会提供支持，该委员会是T32首席研究员。他们评估受训者的进步和受训者的指导。从代表不足的少数族裔中招募受训人员是方案的重点。外部咨询委员会由国际公认的成功调查人员组成，他们目前或曾经是NHLBI资助的T32研究培训项目监督委员会的成员，负责审查该项目，就总体项目方向提供建议，并帮助确保学员成功过渡到学术职业生涯。提供了强大的指导性研究经验。导师和实习生每六个月正式考核一次。我们项目的目标是培养具有成功长期研究事业所需的经验和能力的研究员。

DESCRIPTION (provided by applicant): As a nation, we are facing a growing epidemic of chronic respiratory diseases that have their origins in childhood. Yet, there is a severe shortage of pediatric pulmonologists with the expertise to investigate the basic pathogenesis of respiratory diseases or to develop or critically evaluate new therapies. Out of over 220 NHLBI-funded T32 research training programs, there are only 3 NIH-funded T32 programs dedicated to the research training of pediatric pulmonary physician-scientists. The Duke Multidisciplinary Training Program in Pediatric Lung Disease is designed to develop pediatric pulmonary fellows into well-trained physician-scientists who will be future leaders of basic, translational and clinical research. We have two tracks: a basic research track and a clinical research track. Our basic research track is supported by successful investigators whose research focuses on lung cell and molecular biology, genomics, lung injury, inflammation, immunology and repair, lung development and lung stem cell biology that impact on the science that underlies the pathophysiology of diseases of the lung. Fellows have an intensive hands-on experience in the laboratory and take didactic courses that supplement this training. Our clinical research component is strongly supported by the Duke Clinical Research Training Program, with opportunities for fellows to enroll in the Master's Program in Health Sciences and Clinical Research and graduate programs in Biostatistics and Epidemiology. The rich multidisciplinary environment is supported by all the fellows' participating in three monthly seminar series. The Program leadership are supported by an Internal Advisory Board made up of Duke University Medical Center Faculty who are T32 Principal Investigators. They assess the trainees' progress and the preceptor's mentoring. Recruitment of trainees from underrepresented minorities is a program focus. An External Advisory Board, made up of internationally recognized successful investigators, who are currently or have been on oversight committees for NHLBI-funded T32 research training programs, reviews the program, advises as to the overall program direction and helps ensure successful transition of the trainees into academic careers. A strong mentored research experience is provided. The preceptors and trainees formally assess each other every six months. Our programs' goal is to develop fellows who will have the experience and capabilities needed for a successful long term research career.