Anesthesiology Research Training Program

描述（由申请人提供）：拟议的麻醉学研究培训计划的目标是培养合格的调查麻醉师，重症监护医师和基础科学家，适合入门级，全职，学术教师职位，并为这些人的富有成效的学术生涯做好准备，包括获得校外资金的能力。这部分研究者将满足未来麻醉学和围手术期医学专业的研究需求，包括其他学术麻醉师的培训。该计划旨在为已经完成临床麻醉学住院医师（研究轨道1;传统）的博士后研究员提供实验室研究培训，那些参与综合研究和临床轨道（研究轨道2：综合）的居民，或者是杰出的博士科学家（研究轨道3：基础科学家）明确致力于麻醉学基础研究。三个（资助年1和2）到四个（资助年3至5）研究员将花费至少两年的累积时间在麻醉学系或相关基础科学系的各种实验室之一进行研究。项目教师由33名潜在导师组成，他们具有不同的研究项目（例如分子遗传学，血管生成，离子通道，细胞生理学，粘附分子，类花生酸，运动和呼吸生理学，高血压，自主神经系统，一氧化氮合酶，伤害感受，慢性疼痛，心脏保护，脑循环）。受训人员将有机会使用个别导师的设施，这些导师是由于对医生和基础科学家的研究培训、生产力和校外支持的浓厚兴趣而被选中的。为期两年的承诺将包括通过威斯康星州医学院研究生部和麻醉学系提供的教学核心课程。培训将在通过基础科学家和医生科学家之间的合作促进转化研究的环境中进行。以多样性招生为优先事项的候选人招聘将侧重于那些致力于学术医学事业的个人，并展示在医学和研究生教育和研究经验方面的上级过去表现。这些人将提供未来麻醉学和围手术期医学的领导能力，并扩展作为麻醉学医学亚专业科学基础的知识基础。相关性：越来越多的美国慢性病患者将需要麻醉和手术。然而，参与基础和临床研究的医生-科学家人数出现了不祥的全国性下降，这些研究可以解决围手术期医学的预期挑战。该培训补助金的目的是提供一批优秀的MD和PhD研究人员，他们经过培训，能够进行与麻醉学和围手术期医学相关的精确和无可挑剔的研究。

DESCRIPTION (provided by applicant): The goal of the proposed Anesthesiology Research Training Program is to develop competent investigative anesthesiologists, intensivists, and basic scientists suitable for entry-level, full-time, academic faculty positions and to prepare these individuals for productive academic careers including the ability to acquire extramural funding. This subset of investigators will meet the research needs of the specialty of anesthesiology and perioperative medicine in the future including the training of other academic anesthesiologists. The Program is designed to provide laboratory research training for postdoctoral fellows who have completed their clinical anesthesiology residency (Research Track 1; traditional), those residents who are participating in the integrated research and clinical track (Research Track 2: integrated), or who are outstanding PhD scientists (Research Track 3: basic scientist) with a clear commitment to basic research in anesthesiology. Three (funding years 1 and 2) to four (funding years 3 to 5) fellows will spend at least two years cumulative time in research in one of a variety of laboratories in the Department of Anesthesiology or in allied basic science departments. Program faculty consist of 33 potential mentors with diverse research programs (e.g. molecular genetics, angiogenesis, ion channels, cell physiology, adhesion molecules, eicosanoids, exercise and respiratory physiology, hypertension, autonomic nervous system, nitric oxide synthase, nociception, chronic pain, cardioprotection, cerebral circulation). The trainees will have access to the facilities of the individual mentors who have been selected because of a keen interest in research training of physician and basic scientists, productivity and extramural support. The two year commitment will include a didactic core curriculum offered through the Division of Graduate Studies of the Medical College of Wisconsin and within the department of Anesthesiology. The training will occur in an environment that fosters the conduct of translational investigations through collaborations between basic and physician scientists. Recruitment of candidates with diversity enrollment as a priority will focus on those individuals dedicated to a career in academic medicine and demonstrating a superior past performance in medical and postgraduate education and experience in research. These individuals will provide the leadership envisioned for anesthesiology and perioperative medicine in the future and extend the foundation of knowledge serving as a scientific base for the medical subspecialty of anesthesiology. RELEVANCE: A growing number of Americans with chronic illness will require anesthesia and surgery. However, there has been an ominous national decline in the number of physician-scientists participating in basic and clinical research that could address anticipated challenges in perioperative medicine. The purpose of this Training Grant is to provide a subset of outstanding MD and PhD investigators trained to conduct precise and impeccable research of relevance to anesthesiology and perioperative medicine.