Training in the Neurobiology of Movement and Rehabilitation Sciences

描述（由申请人提供）：本提案的目标是为西北大学在西北大学跨部门神经科学（NUIN）项目的保护下创建的一个新的运动和康复科学（MRS）跨学科项目获得支持。NUIN-MRS计划的使命是培养具有临床和生命/应用科学背景的学生成为基础，转化或临床研究的康复科学家。这些康复科学家将有能力整合MRS中涉及的各个学科的知识，包括神经科学和生理学，工程学和临床科学。培训计划将侧重于运动和康复科学的神经生物学，有三个主要目标：1)理解运动行为和障碍的神经生物学，2)识别和解决MRS定量方法的需求，3)将这些知识应用于有效的康复干预措施的开发。西北大学在运动控制、运动残疾和恢复以及神经重组的研究方面有着悠久而公认的历史。从关注运动和运动障碍控制的基础动物和人类研究到针对这些运动障碍的新型康复干预措施的发展，在这些领域进行了不同层次的广泛研究。该计划的跨学科性质将允许临床研究人员与基础科学和应用科学研究人员之间的密切互动，为从实验室到临床的转化研究培训提供独特的机会。pi计划在培训计划的第一年总共支持4名博士生，在第2-5年每年支持7名实习生。该项目将为每位学员提供为期两年的支持。

DESCRIPTION (provided by applicant): The goal of this proposal is to attain support for a new interdisciplinary program in Movement and Rehabilitation Sciences (MRS), created at Northwestern University under the umbrella of the Northwestern University Interdepartmental Neuroscience (NUIN) program. The mission of the NUIN-MRS program is to train students with clinical and life/applied science backgrounds to become rehabilitation scientists in basic, translational or clinical research. These rehabilitation scientists will have the ability to integrate knowledge from the various disciplines involved in MRS, including neuroscience and physiology, engineering and clinical sciences. The training program will focus on the neurobiology of movement and rehabilitation sciences, with three main goals: 1) understanding the neurobiology of movement behavior and disorders, 2) identifying and addressing the need for quantitative methods in MRS, and 3) applying this knowledge to the development of effective rehabilitation interventions. Northwestern University has a long and recognized history in the study of motor control, motor disability and recovery, and neural reorganization. Extensive research is performed in these areas at various levels, from basic animal and human studies focused on the control of movement and movement disorders to the development of novel rehabilitation interventions that address these movement disorders. The interdisciplinary nature of the program will allow close interaction between clinical investigators and basic and applied sciences investigators, providing a unique opportunity for training in translational research, going from the laboratory to the clinic. The PIs intend to support a total of 4 predoctoral students in year 1 of the training program and 7 trainees in each of years 2-5. The program will provide support for a total of two years for each trainee. PUBLIC HEALTH RELEVANCE: The number of individuals with disabilities and the extent of the disabilities continue to increase with a clear impact on the need for developing better and more effective rehabilitation interventions. The proposed NUIN-MRS PhD program will train rehabilitation scientists based on solid fundamental science principles combined with quantitative methods to allow them to establish research programs to develop effective rehabilitation interventions and, more importantly, transfer them to the clinic.