LIPOATROPHY AND NEUROPATHY COHORT (LINC) STUDY

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本研究的具体目的是确定接受NRTI治疗的HIV感染者中通过血浆F2-异前列烷水平测量的氧化应激增加的患病率和发生率，并确定氧化应激是否与脂肪营养和周围神经病变的变化相关。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The specific aim of this study is to determine the prevalence and incidence of increased oxidant stress as measured by plasma F2-isoprostane levels in HIV- infected persons receiving NRTI therapy, and to determine if oxidant stress is associated with changes in lipatrophy and peripheral neuropathy.