Core H: AIDS Specimen Bank Core

艾滋病标本库(ASB)核心提供专业收集和冷冻保存的生物 将样本链接到详细的临床信息，以实现多学科研究的桥梁 以实验室为基础的基础科学，包括临床、行为和流行病学调查。ASB CORE对CFAR的翻译研究工作仍然至关重要，并已寻求扩大 它提供的服务，与CFAR开创的创新实验方向保持同步 调查人员。在本赠款周期中，艾滋病标本库核心处理了超过127,000份 样本，贡献了48篇发表的手稿，提供了21种不同类型的生物样品 处理和储存，并支持由17名调查员领导的22项调查。核心的回应 针对CFAR调查人员不断变化的需求，引入了2种新的存储方式，并积极 支持CFAR的科学优先事项，包括艾滋病毒感染和健康的长期后果 差距。 ASB享有卓越的声誉，从未因冷冻机故障而丢失过一份标本， 地震或停电。ASB的最先进的库存系统还可以快速定位单个 在银行的25个超低冷冻箱和13个液氮冷冻箱中，有一个冷冻瓶。ASB继续寻求新的 方法通过改变标本的加工和冷冻工艺，提高标本在冷冻保存过程中的存活率。 根据对加州大学旧金山分校-格拉德斯通CFAR调查人员的需求调查，ASB将扩大类型 它为基础和翻译研究处理和存储的标本。ASB还将提供其 支持所有CFAR成员的服务，包括那些设在国内或国际地点的成员。 加州大学旧金山分校艾滋病标本库(ASB)通过以下方式支持CFAR的整体使命 整个加州大学旧金山分校艾滋病毒研究界对生物储存库的需求。我们将通过以下方式实现这一目标 1)继续提供高质量的生物样品加工、管理和储存 种类繁多的科学家； 2)为早期研究人员、研究人员和高级研究人员提供咨询和培训 受训人员； 3)投资新的方法以提高标本的生存能力；以及 4)将Core过渡到数据和样本管理的新技术解决方案。

The AIDS Specimen Bank (ASB) Core provides expertly collected and cryopreserved biological specimens linked to detailed clinical information to enable multidisciplinary research bridging laboratory-based basic science with clinical, behavioral, and epidemiological investigations. The ASB Core remains crucial to the CFAR translational research effort and has sought to expand the range of services it provides, keeping pace with the innovative new experimental directions initiated by CFAR investigators. In the current grant cycle, the AIDS Specimen Bank Core processed over 127,000 samples, contributed to 48 published manuscripts, provided 21 different types of biospecimen processing and storage, and supported 22 investigations led by 17 investigators. The Core responded to the changing needs of CFAR investigators by introducing 2 new storage methods and actively supported CFAR scientific priorities including long-term consequences of HIV infection and health disparities. ASB has an outstanding reputation for never having lost a specimen due to freezer malfunction, earthquakes, or power outages. ASB's state of the art inventory system can also quickly locate a single cryovial among the bank's 25 ultra-low and 13 liquid nitrogen freezers. ASB continues to seek new methods to improve specimen viability during cryostorage through changes in processing and freezing. Based on surveys of the needs of the UCSF-Gladstone CFAR investigators, ASB will expand the type of specimens it processes and stores for basic and translational research. ASB will also provide its services to support all CFAR members, including those based at either domestic or international sites. The UCSF AIDS Specimen Bank (ASB) supports the overall CFAR mission by addressing the biorepository needs of the entire UCSF HIV research community. We will achieve this goal by 1) Continuing to provide high-quality biospecimens processing, management and storage to a wide variety of scientists; 2) Offering consultation and training for early-career investigators, research staff, and advanced trainees; 3) Investing in new methods to improve specimen viability; and 4) Transitioning the Core to a new technology solution for data and specimen management.