Women and HIV: Translation of Research into Practice

摘要 在这份为期5年的肯尼亚医学研究所(KEMRI)和哥伦比亚大学的续签申请中 华盛顿(UW)题为《妇女与艾滋病毒：将研究转化为实践》的计划将继续建立 预防肯尼亚和撒哈拉以南地区妇女和少女新感染艾滋病毒的研究能力 并优化对这一高危弱势群体的护理和治疗。减少突发事件感染 并确保艾滋病毒携带者健康长寿，有必要进行当地相关研究 这解决了知识差距，并为国家指南、临床实践和政策提供了信息。它也是必不可少的 社区和当地卫生官员参与确定最紧迫的问题并找到 解决这些问题的可行、可持续和创新的解决方案。拟议的培训计划的主要目标是 为了在KEMRI和肯尼亚卫生部(MOH)建设侧重于艾滋病毒的实施科学方面的能力， 妇女和青少年，同时建立与青春期女孩和年轻妇女社区的桥梁(AGYW)， 当地卫生官员和其他负责医疗实践和服务提供的组织。KEMRI‘s 坚定致力于开展研究，为服务提供提供信息并改善国民健康结果 为该方案提供了坚实的基础，该方案将继续由Carey Farquhar和 伊丽莎白·布库西。法夸尔博士是威斯康星大学全球健康、医学和流行病学教授 被任命为公共卫生学院负责教育的副院长。布库西博士是以下机构的首席研究官 KEMRI接受过产科、妇科和流行病学家的培训，在威斯康星州大学获得公共卫生硕士和博士学位。这个 First Aim建立在成功的前4年培训计划的基础上。七名肯尼亚人得到了Long-Long- 在此期间的学期训练：4英里/小时，2个博士学位，1英里/博士学位。此外，有5名学员完成中- 在威斯康星州大学接受学期、非学位培训。在接下来的5年里，我们建议资助更多的博士级别的国内培训， 支持来自KEMRI或MOH的6名学员在华盛顿大学攻读实现科学博士学位 内罗毕。为了确保考生的渠道，我们还将支持威斯康星大学时速5英里的实习生和为期5年的证书 受训人员将主要在肯尼亚工作，并在西雅图参加为期1个月的课程，然后是研讨会 以及在肯尼亚的威斯康星大学远程学习课程。第三个目标将把培训的范围扩大到更多的人 KEMRI和卫生部工作人员通过提供为期一周的实施科学、赠款撰写和手稿课程 准备工作。将AGYW社区成员与KEMRI和卫生部聚集在一起的会议 将向研究人员和县卫生主任提供帮助，以促进社区参与当地护理， 肯尼亚西部的治疗和预防，那里的青少年和妇女患癌症的风险高得令人无法接受 爱滋病毒。利用威斯康星大学成熟的培训方法，该计划将建立非常需要的 在KEMRI和卫生部实施科学研究能力，并为改变艾滋病毒的面貌做出贡献 肯尼亚的流行病。

ABSTRACT In this 5-year renewal application for the Kenya Medical Research Institute (KEMRI) and University of Washington (UW) program entitled, Women and HIV: Translation of Research into Practice, will continue to build research capacity to prevent new HIV infections among women and adolescent girls in Kenya and sub-Saharan Africa and optimize care and treatment for this high-risk, vulnerable population. To reduce incident infections and ensure long, healthy lives for persons living with HIV, it is necessary to conduct locally relevant research that addresses the know-do gap and informs national guidelines, clinical practice and policy. It is also essential that communities and local health officials participate in identifying the most pressing problems and in finding feasible, sustainable and innovative solutions to address them. The proposed training program’s primary goal is to build capacity at KEMRI and the Kenya Ministry of Health (MOH) in implementation science focused on HIV, women and adolescents, while creating bridges to communities of adolescent girls and young women (AGYW), local health officials, and other organizations responsible for healthcare practice and service delivery. KEMRI’s strong commitment to conducting research that informs service delivery and improves national health outcomes in Kenya provides a strong foundation for the program, which will continue to be led by Drs. Carey Farquhar and Elizabeth Bukusi. Dr. Farquhar is a UW Professor of Global Health, Medicine, and Epidemiology recently appointed Vice Dean for Education in the School of Public Health. Dr. Bukusi is a Chief Research Officer at KEMRI who trained as an obstetrician-gynecologist and epidemiologist, earning her MPH and PhD at UW. The first aim builds on the successful first 4 years of the training program. Seven Kenyans received support for long- term training during this period: 4 MPH, 2 PhD, and 1 MPH/PhD. In addition, 5 trainees completed medium- term, non-degree training at UW. In the next 5 years, we propose to fund more doctoral level training in-country, supporting 6 trainees from KEMRI or MOH to pursue a PhD in implementation science at the University of Nairobi. To ensure a pipeline of candidates, we will also support 5 MPH trainees at UW and 5 year-long certificate trainees who will be based primarily in Kenya and take 1 month of coursework in Seattle, followed by workshops and UW distance-learning courses in Kenya. The third aim will extend the reach of training to a greater number of KEMRI and MOH staff by providing 1-week courses on implementation science, grant writing, and manuscript preparation. Conferences that bring together members of the AGYW community with KEMRI and MOH researchers and county health directors will be offered to promote community engagement in local care, treatment and prevention in Western Kenya, where adolescents and women are at unacceptably high risk for HIV. Using UW’s well-established approaches to training, this program will establish greatly needed implementation science research capacity at KEMRI and MOH, and contribute to changing the face of the HIV epidemic in Kenya.