Non-Haemolytic Friulimicins for the Treatment of Multi-Drug Resistant Bacteria
Non-Haemolytic Friulimicins for the Treatment of Multi-Drug Resistant Bacteria
批准号:
nhmrc : 1026921
负责人:
Dr Mark Butler
金额:
$36.85万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2012
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2012-01-01 至 2014-12-31
中文摘要
我们正在开发一种名为friulimicin的新型抗生素,以对抗在医院和社区引起严重感染的ïsuperbugsÍ。我们将对该药进行优化,以靶向耐甲氧西林金黄色葡萄球菌(MRSA)、耐万古霉素肠球菌(VRE)和耐药肺炎链球菌(DRSP)。我们还将研究如何将这种药物用于治疗肺炎等肺部感染,在这种情况下,抗生素比现有的抗耐药细菌药物效果更好。
英文摘要
We are developing a new antibiotic, called friulimicin, to combat the ïsuperbugsÍ that cause serious infections in hospitals and the community. We will optimize the drug to target MRSA (methicillin resistant Staphylococcus aureus) VRE (vancomycin resistant enterococci) and DRSP (drug resistant Streptococcus pneumoniae). We will also investigate how the drug can be used for treatment of lung infections such as pneumonia, where the antibiotic can work much better than existing drugs against resistant bacteria.
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