Career Enhancement Program

摘要-职业提升计划（CEP） 马约诊所卵巢癌SPORE的目的是刺激，组织和促进严格的 转化研究，这将有意义地减少卵巢癌的负担。这个过程的关键部分 是为了提高卵巢癌研究的质量和深度。6-10年级 5名个人获得了职业提升计划（CEP）奖项，并获得了1-2个 年的资助（一名获奖者获得两年的资助;四名获奖者获得1年的资助），指导团队，以及 访问SPORE资源。我们的获奖者非常成功，有39篇同行评审的手稿 由6-10年级获奖者出版，3人成功获得后续资金。所有五年6-10 获奖者依赖于生物化学和生物信息学核心（核心C），四名获奖者还与 生物样本和患者登记（核心B），以及三个动物模型核心（核心D）。最终 职业提升计划（CEP）的目标仍然是识别和指导新的 以及培养卵巢癌研究人员， 转化研究人员以及吸引建立谁希望重新关注卵巢癌的科学家。 CEP为一年的支持提供高达100，000美元的资金（50，000美元来自SPORE基金， 马约诊所癌症中心提供50 000美元）;根据进展情况，第二年可能继续 平移轨迹特别强调吸引任职人数不足的高素质个人 包括妇女、少数民族和残疾人。识别和选择CEP 获奖者是通过严格的审查过程，其次是密集的辅导，融入 持续的SPORE活动，并密切监督每个人的进展。除了一个主要的导师， 获奖者在临床、基础或人口科学方面有必要的补充导师，以确保 发展翻译研究事业。这充分利用了 马约环境。CEP董事会向马约卵巢诊所执行委员会报告 癌症孢子。在下一个资助期内，卵巢孢子CEP将继续保持：（1）A 严格的候选人甄选制度;（2）由初级导师全面指导学员;（3）支持 通过一个科学指导小组（每个获奖者的个别培训生指导委员会）， 在每个获奖者感兴趣的领域具有专业知识的调查人员;以及（4）完全融入SPORE， 包括访问所有科学核心。马约诊所提供了一个特殊的环境， 在卵巢癌转化研究的职业生涯。CEP使我们能够识别，指导和支持年轻人 他们将成为卵巢癌研究的未来领导者。

ABSTRACT – CAREER ENHANCEMENT PROGRAM (CEP) The purpose of the Mayo Clinic SPORE in Ovarian Cancer is to stimulate, organize and facilitate rigorous translational research that will meaningfully reduce the burden of ovarian cancer. A critical part of this process is to increase the quality and depth of the translational investigator base in ovarian cancer. During Years 6-10 of funding, five individuals received Career Enhancement Program (CEP) awards and were supported with 1-2 years of funding (one awardee with 2 years of funding; four with 1 year of funding), mentoring teams, and full access to SPORE resources. Our awardees have been highly successful, with 39 peer-reviewed manuscripts published by Year 6-10 awardees and 3 have successfully secured subsequent funding. All five Year 6-10 awardees relied upon the Biostatisics and Bioinformatics Core (Core C), four awardees also partnered with the Biospecimens and Patient Registry (Core B), and three with the Animal Models Core (Core D). The ultimate objectives of the Career Enhancement Program (CEP) continue to be the identification and mentoring of new and developing investigators in ovarian cancer who demonstrate clear potential to become independent translational researchers as well as attracting established scientists who wish to refocus on ovarian cancer. The CEP provides up to $100,000 for one year of support ($50,000 from SPORE funds and a matching $50,000 from Mayo Clinic Cancer Center); a second year is possible based on progress and continued translational trajectory. Special emphasis is placed on attracting highly qualified individuals underrepresented in medicine, including women, minorities, and persons with disabilities. Identifying and selecting CEP awardees is accomplished through a rigorous review process, followed by intense mentoring, integration into ongoing SPORE activities and close oversight of each individual’s progress. In addition to a primary mentor, awardees have complementary mentors in clinical, basic or population sciences necessary to ensure development of a translational research career. This capitalizes on numerous strengths present within the Mayo environment. The CEP directorship reports to the Executive Committee of the Mayo Clinic Ovarian Cancer SPORE. During the next funding period, the Ovarian SPORE CEP will continue to maintain: (1) A stringent candidate selection system; (2) comprehensive trainee guidance by a primary mentor; (3) support through a scientific mentoring group (each awardee’s Individual Trainee Mentorship Committee) comprised of investigators with expertise in each awardee‘s area of interest; and (4) full integration into the SPORE, including access to all scientific Cores. Mayo Clinic provides an exceptional environment for developing careers in translational research in ovarian cancer. The CEP allows us to identify, mentor, and support young investigators who will become future leaders in ovarian cancer research.