An Observational Study of Cardiac Critical Care Management in Multidisciplinary and Cardiac Intensive Care Units

在过去的半个世纪里，冠状动脉监护室已经从心肌梗死后的护理和心律失常的初步检测和治疗发展到目前的心脏重症监护病房（CICU）。当代CICU为日益老龄化和复杂的患者群体提供护理。现代CICU的临床环境包括与晚期心脏疾病相关的危重合并症和多系统器官功能障碍，包括顽固性心力衰竭、缺血、心律失常、心源性休克，甚至免疫抑制心脏移植患者的感染性休克。

During the past half century, the coronary care unit has evolved from a site for post myocardial infarction care and primary detection and treatment of arrhythmias to its current form as a cardiac intensive care unit (CICU). The contemporary CICU provides care for an increasingly aging and complex patient population. The clinical environment of the modern CICU encompasses critical co-morbid conditions and multi system organ dysfunction associated with advanced cardiac conditions ranging from refractory heart failure, ischemia, and dysrhythmias through cardiogenic shock and even septic shock in immunosuppressed heart transplant patients. The protocol related to this project is a multicenter study that was approved by the National Heart Lung and Blood Institutional Review Board in May 2018. The study is sponsored by the Academic Executive and Steering Committees of the Critical Care Cardiology Trials Network (CCCTN) and coordinated by The TIMI Study Group at Brigham and Women's Hospital, Harvard Medical School, Boston, MA. At the NIH Clinical Center (CC), data collection will capture information from records of adult patients with cardiac conditions admitted to the multidisciplinary ICU during a 2 month "snap-shot" period. The study will involve only a review of patient records and will not use specimens or involve participant contact. Medical records will be reviewed from participants enrolled in NIH protocols related to their underlying disease(s). This study will not involve any interventions or changes to the patients care. The study involves collection and analysis of information obtained as part of routine clinical care as documented in the medical record. Data will be collected for eligible subjects admitted to the Clinical Center after the protocol approval date. Only de-identified data will be submitted to the Data Coordinating Center. The information resulting from inclusion in this study will not have any health or medical implications for subjects and privacy standards will be observed rigorously. During the current reporting period 19 patient records from the NIH CC ICU were entered into CCCTN registry. Over the life of the protocol (as of August 2020) a total of 39 NIH CC ICU patient records have been entered into the CCCTN registry which contains information on over 12,500 patients of which about 4,500 were obtained during the 2019-20 reporting period.