课题基金 / 基金详情

Admin Core

Admin Core
管理核心
批准号:
10588206
负责人:
Samithamby Jeyaseelan
金额:
$71.02万
依托单位国家:
美国
项目类别:
财政年份:
2019
资助国家:
美国
项目状态:
已结题
起止时间:
2019-01-02 至 2024-12-31

项目摘要

项目成果

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中文摘要
翻译
项目总结 路易斯安那州立大学肺生物学和疾病中心(又名肺眼镜蛇)的目标 (LSU)是为了阐明危及生命的急性和慢性呼吸道疾病的分子和细胞发病机制。 影响人类人口的疾病。行政核心(AC)将提供行政支持, 组织、协调和有效的管理是确保肺科医生和 我们有前途的初级调查员(PJI)。该核心还将提供会计支持,以确保 适当的财政和科学监督、监测和遵守联邦和机构拨款 管理规定。Cobre将在#年在病理生物科学(PBS)范围内实施 与路易斯安那州立大学兽医学院(LSU)比较生物医学(CBS)合作 支持向量机)。在目前的资金环境下,肺眼镜蛇的成功取决于许多因素:1)和 卓越的个性化指导计划;2)翻新的动物收容和研究空间,拥有最先进的 最先进的设施;3)通过科学核心获得现代设备和尖端技术;4) 消除PJI过多的行政和服务负担;以及5)促进机构内部的合作 以及路易斯安那州的机构之间通过NIGMS资助的INBRE、Cobre和LA CATS。为了促进 PJI的职业发展,我们聚集了具有出色记录的资深科学家服务于 内部(IAC)和外部咨询(EAC)以及指导委员会(MC)。PJI的个人项目 将得到肺免疫病理学(PIP)和分子生物学(MB)核心的支持,以利用 在生物医学研究方面具有出色的本土优势。为了确保肺科布雷的成功,我们开发了一种 建立(第一阶段-5年)、扩大(第二阶段-5年)和维持(第三阶段-5年)的15年战略计划 几年)Long Cobre成为一个独立的中心,并获得国内和国际的认可 通过多个资金来源,如联邦、州、基金会、行业和大学。
英文摘要
PROJECT SUMMARY The objective of the Center for Lung Biology and Disease (aka Lung COBRE) at Louisiana State University (LSU) is to elucidate the molecular and cellular pathogenesis of life-threatening acute and chronic respiratory diseases affecting human population. The Administrative Core (AC) will provide administrative support, organization, coordination, and efficient management necessary to ensure the success of the lung COBRE and of our Promising Junior Investigators (PJIs). This Core will also provide accounting support that will ensure appropriate fiscal and scientific oversight, monitoring, and compliance with federal and institutional grant management regulations. The COBRE will be administered within Pathobiological Sciences (PBS) in collaboration with Comparative Biomedical Sciences (CBS) in the LSU School of Veterinary Medicine (LSU SVM). In the current funding climate, success for the lung COBRE depends on numerous factors: 1) an outstanding personalized mentoring program; 2) renovated animal holding and research space with state-of- the-art facilities; 3) access to modern equipment and cutting-edge technology through Scientific Cores; 4) remove excessive administrative and service burdens for PJIs; and 5) foster collaborations within the institution and between institutions in Louisiana through NIGMS-funded INBRE, COBRE and LA CaTS. To promote the career development of PJIs, we have assembled senior scientists with outstanding track record to serve on Internal (IAC) and external advisory (EAC) as well as mentoring committees (MC). The PJI’s individual projects will be supported by Pulmonary Immunopathology (PIP) and Molecular Biology (MB) cores to leverage excellent local strengths in biomedical research. To ensure success of the lung COBRE, we have developed a 15-year strategic plan to establish (Phase I - 5 years), expand (Phase II - 5 years), and sustain (Phase III - 5 years) lung COBRE to become an independent center and to attain national and international recognition through multiple sources of funding, such as federal, state, foundations, industry, and university.
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Host Immunity in Sepsis-Induced Systemic Infection
Host Immunity in Sepsis-Induced Systemic Infection
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