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中文摘要
翻译
摘要 功能愿景核心 功能视觉核心将提供询问实验动物视觉功能所需的技术 P30科尔眼科视力研究核心参与的研究人员。功能愿景核心将提供状态 对老鼠和斑马鱼的视觉功能进行ART评估。这将包括视觉电生理测试,如 如视网膜电信号(ERG)、图形视网膜电信号(ERG)、视觉诱发电位(VEP)和视觉行为分析 视动反射(OKR)、视运动反射(OMR)和阈值测量。总而言之,这些化验询问了 视觉功能从光感受器中的光检测到大脑中的信号整合和解释。这 CORE将支持NEI R01资助的调查人员,帮助调查人员获得额外NEI R01拨款的数据 提交,促进R01资助的调查人员之间的协作互动,吸引来自其他国家的调查人员 各部门研究视觉系统,并成为吸引更多视力的宝贵部门资源 科学家加入我们的项目,因为我们扩大了我们的研究人员队伍。
英文摘要
Abstract Functional Vision Core The Functional Vision Core will provide the technologies required to interrogate visual function in experimental animals to the investigators involved in this P30 Cole Eye Vision Research Core. The Functional Vision Core will provide state of the art assessment of visual function in mice and zebrafish. This will include visual electrophysiological assays such as the electroretinogram (ERG), pattern ERG, the visual evoked potential (VEP), and visual behavior assays such as the optokinetic reflex (OKR), optomotor reflex (OMR) and threshold measurement. Collectively, these assays interrogate visual function from light detection in the photoreceptors to signal integration and interpretation within the brain. This Core will support NEI R01-funded investigators, help investigators obtain data for additional NEI R01 grant submissions, foster collaborative interactions between R01-funded investigators, attract investigators from other departments to research on the visual system and be a valuable departmental resource in attracting additional vision scientists to our program as we expand our research faculty.
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Inflammatory Signaling and Regeneration in Zebrafish models of Retinal Degeneration
  • 批准号:
    10751153
  • 项目类别:
  • 资助金额:
    $54.15万
  • 财政年份:
    2023
  • 负责人:
    Brian D Perkins
  • 依托单位:
Stimulating Retina Regeneration from Muller Cells in Progressive Retinal Degenerations
  • 批准号:
    10379368
  • 项目类别:
  • 资助金额:
    $51.01万
  • 财政年份:
    2020
  • 负责人:
    Brian D Perkins
  • 依托单位:
Core D Functional Vision Module
  • 批准号:
    10670899
  • 项目类别:
  • 资助金额:
    $5.02万
  • 财政年份:
    2016
  • 负责人:
    Brian D Perkins
  • 依托单位:
The Role of Wrb in Vertebrate Ribbon Synapse Formation
  • 批准号:
    8301306
  • 项目类别:
  • 资助金额:
    $0.0万
  • 财政年份:
    2012
  • 负责人:
    Brian D Perkins
  • 依托单位:
海外基金