Timing Of Exercise In Concussed Rat Athletes

项目摘要/摘要 对于青少年和年轻的成年运动员来说，反复脑震荡是一个日益严重的问题。试验性的 其中一个问题是，没有人在“运动员”模式中解决这一问题。越来越多的证据 表明那些经常锻炼的人(运动员)的大脑与那些经常锻炼的人的大脑非常不同 久坐不动。这些差异将影响“运动员大脑”对脑震荡损伤的反应。在这 应用我们开发了一个小鼠模型来研究脑震荡损伤和康复的影响 在雄性和雌性大鼠的运动员脑和非运动员脑之间。这项工作不仅将 提供有关脑损伤研究的重要信息，但强调运动在 青春期健康。

Project Summary/Abstract Repeat concussions are a growing concern for adolescents and young adult athletes. Experimentally one of the problems is that no one has been addressing this in an “athlete” model. Growing evidence shows that the brains of those that exercise regularly (athletes) are very different than those that are sedentary. These differences will affect how the “athlete brain” responds to concussive injuries. In this application we have developed a rathlete model to study the effects of concussive injuries and recovery between the athlete brain and non-athlete brain in both male and female rats. This work will not only provide important information regarding brain injury research, but emphasize the role of exercise in adolescent health.