Administrative Core

项目摘要 临床研究核心中心（CCCR）的行政核心，以改善少数民族健康， 南卡罗来纳州医科大学的风湿性疾病（IMHRD，发音为IaMHeaRD）将提供 领导和管理的中心，并实施试点项目计划，将完全资助 机构的承诺。本CCCR的使命是推进临床方面的知识 患有系统性狼疮或有发生系统性狼疮风险的非裔美国人的护理和健康结果 红斑、硬皮病和其他使人衰弱的风湿性疾病。的总体目标 行政核心是：（a）确保工具、服务的质量、有效性、可获得性和适用性， CCCR核心的样本、数据和其他输出，（B）促进基础、转化和临床之间的互动 科学家在MUSC和超越有效地专注于推进预防，诊断和治疗 （c）促进研究成果和资源的适当传播。实现 为实现这些目标，我们将努力实现以下具体目标：为CCCR提供领导; 2。协调和 管理CCCR的组织、业务和财务职能以及评估活动; 3.杠杆 机构基础设施资源; 4.制定和管理多年评估计划; 5.加强和 扩大强有力、有效的沟通、传播和外联活动， 卫生专业人员、科学界和公民社区成员之间的互动; 6.提供 有竞争力的试点项目。该核心将由医学博士加里吉尔克森指导，并由两名 副董事，吉姆奥茨，医学博士，和理查德银，医学博士，执行委员会，其中包括核心领导人 和研究界代表，一个内部咨询委员会，其中包括机构 利益相关者和患者倡导者，以及包括该领域专家在内的外部咨询委员会， 领导其他NIAMS中心的经验。行政核心工作人员将提供行政支助， 该中心，管理和监督财务，协调会议和行动项目，并接口 与NIAMS的工作人员和机构人员。行政核心还将支持教育和 开展宣传活动，提高中心在MUSC和当地社区的知名度和影响力 并提供一个交流和交换研究思想的论坛。行政核心将培养一个 充满活力的，互动的临床和转化研究计划，将促进我们的知识和资源 用于改善风湿性疾病（特别是全身性疾病）的预防、诊断、治疗和健康结果 红斑狼疮（SLE）和系统性硬化症（SSc），发生率明显更高， 严重程度在非洲裔美国人比其他种族和族裔群体在美国。

PROJECT SUMMARY The Administrative Core of the Core Center for Clinical Research (CCCR) for Improving Minority Health in Rheumatic Diseases (IMHRD, pronounced IaMHeaRD) at the Medical University of South Carolina will provide leadership and management for the center and implement a pilot projects program that will be funded entirely with institutional commitments. The mission of this CCCR is to advance knowledge with respect to the clinical care and health outcomes of African Americans who have, or who are at risk of developing, systemic lupus erythematosus, scleroderma and other debilitating rheumatic diseases. The overarching goals of the Administrative Core are to: (a) ensure the quality, validity, accessibility and applicability of the tools, services, samples, data and other output of the CCCR cores, (b) foster interactions among basic, translational and clinical scientists at MUSC and beyond to focus effectively on advancing prevention, diagnosis and treatment of rheumatic diseases, and (c) facilitate appropriate dissemination of research results and resources. To achieve these goals, we will pursue the following specific aims: 1. Provide leadership for the CCCR; 2. Coordinate and manage CCCR organizational, operational and financial functions and evaluative activities; 3. Leverage institutional infrastructure resources; 4. Develop and manage a multi-year Evaluation Plan; 5. Strengthen and expand robust, effective communication, dissemination and outreach activities, fostering mutually productive interactions among members of health professional, scientific and citizen communities; and 6. Provide a competitive Pilot Projects Program. This core will be directed by Gary Gilkeson, MD, with assistance from two Associate Directors, Jim Oates, MD, and Richard Silver, MD, an Executive Committee that includes core leaders and Research Community representatives, an Internal Advisory Committee that includes institutional stakeholders and patient advocates, and an External Advisory Committee that includes experts in the field with experience leading other NIAMS centers. The Administrative Core staff will provide administrative support for the center, administering and monitoring the finances, coordinating meetings and action items, and interfacing with NIAMS staff and institutional personnel. The Administrative Core also will support educational and dissemination activities to enhance the visibility and impact of the center within MUSC and the local community and provide a forum for communicating and exchanging research ideas. The Administrative Core will nurture a vibrant, interactive program of clinical and translational research that will advance our knowledge and resources for improving the prevention, diagnosis, treatment and health outcomes for rheumatic diseases, notably systemic lupus erythematosus (SLE) and systemic sclerosis (SSc), which occur significantly more often and with greater severity in African Americans than in other racial and ethnic groups in the United States.