Administrative Core

项目摘要-行政核心（AC） 印第安纳州阿尔茨海默病研究中心（IADRC）行政核心（AC）的作用是 为中心提供战略规划、管理、资源和监督，以支持其继续 使命。这一作用的重要性是基于美国的国家反倾销计划（NAPA），以预防和 到2025年，通过对病因学、早期发现和治疗方法的创新研究，有效治疗AD。帮助 为了实现这些目标，IADRC提出了IADRC更新申请的四个总体中心目标： (1)支持、加强和扩大针对AD和相关痴呆症发病机制的创新研究， 诊断，治疗和预防;（2）提供关键的研究资源和基础设施，以支持 现有的研究，并使新的创新研究，包括一个良好的特点纵向跟踪 研究参与者队列;（3）大力支持当地，区域和国家/国际痴呆症 研究合作，以促进国家评估、国家ADRC网络、国家适应行动方案和相关联邦的目标 （4）为各级学习者提供与ADRD相关的教育和培训机会， 包括具有不同背景和需求的人。审核委员会负责整体管理及 IADRC的战略方向。中心和AC内部的领导层一直很稳定， Saykin自2013年起担任中心主任。布拉德·格拉泽长期担任IADRC管理员， Sarah货车海登是新的研究运营经理。咨询委员会有六个具体目标：（1）总体而言， AD及相关疾病研究的方向和战略规划。AC将有助于利用现有的 计划和教师的优势，并为科学的增长和影响开发新的机会。它还将 促进各核心之间的整合，以实现主题的连贯性。AC将协调执行委员会， 包括主要领导人提供建议，并帮助实现中心的目标。(2)提供行政支持， 资源管理和监督职能。(3)确保不断评价和监督科学 进步、研究和培训。(4)推进IADRC促进和扩大创新研究的目标， 与AD/ADRD相关的培训和合作学术活动。(5)开发和管理IADRC 发展项目计划，包括征求建议书，健全和公正的审查程序， 和跟踪基于外部资金和出版物的成果指标;以及（6）作为有效的 与重要的外部组织建立联系，促进与其他区域、国家和国际组织的合作， 国际AD研究倡议。这包括与NIA以及NACC，NCRAD， ADNI、DIAN、LEADS、ACTC、ADGC/ADSP、AMP-AD、ADMC/ANOTE、MODEL-AD、ADI-AD和其他 财团。IADRC致力于实现这些目标，以支持和加快以下方面的进展： 应对AD和相关疾病的挑战。

Project Summary – Administrative Core (AC) The role of the Administrative Core (AC) of the Indiana Alzheimer Disease Research Center (IADRC) is to provide strategic planning, management, resources, and oversight for the Center in support of its continued mission. The significance of this role is based on the U.S. National Plan for AD (NAPA), to prevent and effectively treat AD by 2025 through innovative research on etiology, early detection, and therapeutics. To help accomplish these goals the IADRC has proposed four Overall center aims for the IADRC renewal application: (1) Support, enhance, and expand innovative research on AD and related dementias targeting pathogenesis, diagnosis, treatment, and prevention; (2) Provide critical research resources and infrastructure to support existing studies and enable new innovative research, including a well-characterized longitudinally followed cohort of research participants; (3) Strongly support local, regional, and national/international dementia research collaborations to further the goals of the NIA, national ADRC Network, NAPA and related federal priorities; and, (4) Provide educational and training opportunities related to ADRD for learners of all levels, including those with diverse backgrounds and needs. The AC is responsible for overall management and strategic direction of the IADRC. Leadership within the Center and AC has been stable, with Dr. Andrew Saykin serving as the Center Director since 2013. Brad Glazier has long served as IADRC Administrator and Sarah Van Heiden is the new Research Operations Manager. The AC has six specific aims: (1) Overall direction and strategic planning for research on AD and related disorders. The AC will help to leverage existing strengths of programs and faculty and develop new opportunities for scientific growth and impact. It will also foster integration among the cores for thematic cohesion. The AC will coordinate the Executive Committee, including key leaders to advise and help implement the Center goals. (2) Provide administrative support, resource management and oversight functions. (3) Ensure ongoing evaluation and oversight of scientific progress, research and training. (4) Advance the IADRC goals of fostering and expanding innovative research, training and collaborative academic activities related to AD/ADRD. (5) Develop and manage the IADRC Developmental Projects Program, including solicitation of proposals, a robust and impartial review process, and tracking outcome metrics based on external funding and publication; and (6) Serving as an effective interface to important external organizations and promoting collaboration with other regional, national and international AD research initiatives. This includes interaction with the NIA as well as the NACC, NCRAD, ADNI, DIAN, LEADS, ACTC, ADGC/ADSP, AMP-AD, ADMC/ADMP, MODEL-AD, TREAT-AD and other consortia. The IADRC is committed to accomplishing these aims to support and accelerate progress in addressing the challenges of AD and related disorders.